Ovarian Cancer Immunotherapy

Chapter 1: Antibody Therapeutics for Ovarian Carcinoma and Translation to the Clinic
Debra H. Josephs, Heather J. Bax, Giulia Pellizzari, James F. Spicer, Ana Montes, and Sophia N. Karagiannis

Chapter 2: Biological Aspects and Clinical Applications of Serum Biomarkers in Ovarian Cancer
Rouba Ali- Fehmi and Eman Abdulfatah

Chapter 3: Ovarian Cancer Immunity: How Does Immune Suppression Grow Cancer?
Vincent Lavoué, Patrick Legembre, Jean Levêque, Fabrice Foucher, Sébastien Henno, and Florian Cabillic

Chapter 4: Ovarian Tumor Microenvironment and Innate Immune Recognition
Jocelyn Reader, Sarah Lynam, Amy Harper, Gautam Rao, Maya Matheny, and Dana M. Roque

Chapter 5: Adoptive Cell Immunotherapy for Epithelial Ovarian Cancer
Samir A. Farghaly

Chapter 6: Antibody-based Therapy for Ovarian Cancer
Yousef Alharbi, Manish S. Patankar, and Rebecca J. Whelan

Chapter 7: Epitope/Peptide-based Monoclonal Antibodies for Immunotherapy of Ovarian Cancer
Gregory Lee

Chapter 8: Dendritic Cell Vaccine Therapy for Ovarian Cancer
Caitlin Stashwick, Brian J. Czerniecki, Janos L. Tanyi

Chapter 9: Heat Shock Protein Vaccine Therapy for Ovarian Cancer
Hiroyuki Abe, Amane Sasada, Shigeki Tabata, Hiroaki Kawasaki, and Minako Abe

Chapter 10: PD-1 /PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer
Scott Moerdler and Xingxing Zang

Chapter 11: Growth Factors and Their Corresponding Receptors as Targets for Ovarian Cancer Therapy
Anca Maria Cimpean, Andreea Adriana Jitariu, and Marius Raica

Chapter 12: Unique Challenges Facing Immunotherapy of Metastatic Ovarian Cancer
Michelle N. Messmer, Colleen S. Netherby, and Scott I. Abrams

Chapter 13: Clinical Trials of Ovarian Cancer Immunotherapy and Future Directions
Justin M. Drerup, Curtis A. Clark, and Tyler J. Curiel

• Provides overview of basic sciences, and clinical and therapeutic aspects of immunotherapy for ovarian cancer
• Chapters are written by a team of expert contributors from renowned medical institutions around the world
• Ideal resource for clinicians and medical students caring for patients with ovarian cancer

Ovarian Cancer Immunotherapy provides a broad overview of several aspects of basic sciences, and clinical and therapeutic aspects of immunotherapy for ovarian cancer, as well as state-of-the-art information on molecular genetics and biology. Chapters are written by a team of expert contributors from around the world and explore topics such as antibody therapeutics for ovarian carcinoma, emerging serum biomarkers, ovarian cancer immunity, adoptive cell immunotherapy, the biology of dendritic cells, the role of growth factors, and more. Readers will also gain a better understanding of the molecular and cellular events that underlie ovarian cancer immunology. This book is an ideal resource for clinicians, basic medical scientists, graduate basic medical science students, and medical students caring for patients with ovarian cancer, including attending surgeons and physicians, and clinical fellows and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology.

Edited by Samir A. Farghaly, Dept. Obstetrics & Gynecology, Weill Cornell Medical Center

Samir A. Farghaly, MD, PhD is a Professor Obstetrics and Gynecology at the Joan and Sanford I. Weill Medical College, Graduate School of Medical Sciences; Sandra and Edward Meyer Cancer Center; and New York-Presbyterian Hospital/Weill Cornell Medical Center in New York, NY. He received his MD and PhD in molecular biology from London University. Dr. Farghaly is the Founder and Editor-in Chief of Current Trends in Gynecologic Oncology, and The International Journal of Gynecological, Obstetrical, and Reproductive Medicine Research. He is a member of the editorial boards of 18 international medical journals on Gynecological Cancers, Gene Expression and Therapy, Women's Health, and Gynecology.