Imaging in Dermatology

Avci, P. — Hamblin, M. — Gupta, G.

1ª Edición Agosto 2016

Inglés

Tapa blanda

560 pags

900 gr

17 x 24 x null cm

ISBN 9780128028384

Editorial ACADEMIC PRESS

LIBRO IMPRESO

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118,26 €112,35 €IVA incluido

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Agotado

radiología dermatológica | imagen dermatológica

Description

Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies.

Key Features

Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings
Provides knowledge of current and future applications of dermatological imaging and lasers
Coherently structured book written by the experts working in the fields covered

Readership

Dermatologists and other physicians; researchers in the fields of dermatology, radiology, drug delivery and pharmaceutical science, molecular biology, cancer diagnostics and treatment, and biotechnology.

Dedication

List of Contributors

Chapter 1. Introduction to Imaging in Dermatology

Chapter 2. The Role of Clinical Photography in Dermatology

Introduction
The Equipment
The “Art” of Taking Dermatological Clinical Pictures
Why Photographs?
Photographs as an Educational Tool
Photographs as a Diagnostic Tool
Three Additional Aspects That Need to be Considered in This Context
Photography as a Tool for Documentation
Photography as a Tool in Research
Photographs from the Patient's Perspective
Photographs from a Legal Point of View
Photography as an Informative Tool for the General Population
Conclusions

Chapter 3. Dermoscopy

Introduction
Dermoscopy of Melanocytic Skin Tumors
Dermoscopy of Common Benign Nonmelanocytic Skin Tumors
Dermoscopy of Common Malignant Nonmelanocytic Tumors
Dermoscopy in General Dermatology
Conclusion

Chapter 4. Trichoscopy: The Dermatologist's Third Eye

Introduction
Technical Considerations
Dermoscopic Features
Trichoscopy Findings in Common Hair and Scalp Conditions
Conclusion
Abbreviations

Chapter 5. Dermatoscopic Correlates of Nail Apparatus Disease: A Look at the Nail From Another Scope, the Dermatoscope

Introduction
Methods in Nail Dermatoscopy
Dermatoscopy of Nail Pigment Changes (Chromonychia)
Dermatoscopy of Other Nail Changes
Conclusion

Chapter 6. Optical Coherence Tomography for Skin Cancer and Actinic Keratosis

Introduction
Optical Coherence Tomography
The Squamous Spectrum
Basal Cell Carcinoma
Pigmented Nevi and Melanoma
Other Skin Tumors
Conclusion

Chapter 7. Optical Coherence Tomography Imaging of Skin Scarring and Fibrosis

Introduction
Optical Coherence Tomography Imaging of Normal Skin Collagen
Optical Coherence Tomography Imaging of Skin Fibrosis as a Feature of Systemic Sclerosis
Optical Coherence Tomography Imaging of Fibrotic Scars
The Future of Optical Coherence Tomography
Conclusion
Abbreviations

Chapter 8. Polarization Speckles and Skin Applications

Introduction
Skin Surface Roughness Quantification
Melanoma Screening
Electric Field Monte Carlo Simulation
Conclusion
Glossary
List of Acronyms and Abbreviations

Chapter 9. New Developments in Fluorescence Diagnostics

Introduction
Fluorescence History
Fluorescence Principles
Fluorescence Capture and Detection
Image Enhancement
Autofluorescence
Alternative Detection Methods

Chapter 10. Ex Vivo Fluorescence Microscopy: Clinical Applications in Dermatology and Surgical Pathology

Introduction
Contrast Agents
Instrument and Image Acquisition
Application of Ex Vivo Fluorescence Microscopy in Dermatology
Application of Ex Vivo Fluorescence Microscopy in General Surgery
Conclusions
List of Acronyms and Abbreviations

Chapter 11. Coherent Raman Scattering Microscopy in Dermatological Imaging

Introduction
Imaging Skin Structures Using Coherent Raman Scattering
Imaging Drug Penetration and Chemical Diffusion Using Coherent Raman Scattering
Challenges and New Advances of Coherent Raman Techniques in Skin Imaging
Conclusions
List of Acronyms and Abbreviations

Chapter 12. Rapid Real-Time Raman Spectroscopy and Imaging-Guided Confocal Raman Spectroscopy for In Vivo Skin Evaluation and Diagnosis

Introduction
Rapid Real-Time Raman System
Rapid Real-Time Raman System for In Vivo Skin Cancer Diagnosis
Modeling of In Vivo Skin Raman Spectra
Imaging-Guided Confocal Raman Spectroscopy for In Vivo Skin Assessment
Summary

Chapter 13. Surface-Enhanced Raman Spectroscopy for Intradermal Measurements

Introduction
Survey of Intradermal Surface-Enhanced Raman Spectroscopy Approaches
Future Trends of Intradermal Surface-Enhanced Raman Spectroscopy Development
Conclusion
List of Acronyms and Abbreviations

Chapter 14. Broadband Coherent Anti-Stokes Raman Scattering

Introduction
Background
Broadband Coherent Anti-Stokes Raman Scattering
Theory
Experimental Results: Tissue Imaging
Conclusion
List of Abbreviations
Glossary

Chapter 15. In Vivo Reflectance Confocal Microscopy in Dermatology

Introduction
The Technology: Reflectance Confocal Laser Microscope
Normal Skin Under Reflectance Confocal Microscopy
Reflectance Confocal Microscopy for Pigmented Tumors
Reflectance Confocal Microscopy for Epithelial Tumors
Reflectance Confocal Microscopy for Inflammatory Lesions
Reflectance Confocal Microscopy for Monitoring Treatment Response of Skin Tumors
Reflectance Confocal Microscopy for Infestations and Infections
Reflectance Confocal Microscopy Application in Cosmetics
Conclusions
List of Abbreviations

Chapter 16. Hyperspectral and Multispectral Imaging in Dermatology

Introduction
Tissue Optics Principles
Hyperspectral/Multispectral Imaging Systems
System Performance
Applications in Dermatology
Summary

Chapter 17. Diffuse Reflectance Spectroscopy and Imaging

Introduction
Principles of Diffuse Reflectance
Diffuse Reflectance Methods
Applications of Diffuse Reflectance in Dermatology
Conclusion
List of Acronyms and Abbreviations
Glossary

Chapter 18. Spectral Imaging in Dermatology

Outline
Introduction
Skin Specimens Ex Vivo
Spectral Imaging of Histological Sections with Conventional Microscopes
Reflectance and Absorbance Spectroscopy of Intrinsic Skin Contrast
Multiphoton Microscopy and Autofluorescence
Second Harmonic Generation Imaging in Conjunction with Two-Photon Excited Fluorescence
Fluorescence Lifetime Imaging
Pump-Probe Microscopy
Raman Spectroscopy
Computational Analytical Tools
Conclusion
List of Abbreviations

Chapter 19. Applications of Multiphoton Microscopy in Dermatology

Introduction
Multiphoton Microscopy Spectroscopy and Imaging Theory Fundamentals
Skin Photophysical and Photochemical Properties and Multiphoton Dermal Imaging
Design Considerations of Multiphoton Microscopy
Applications of Multiphoton Microscopy in Different Areas of Dermatological Studies
Conclusion

Chapter 20. Nonlinear Microscopy in Clinical Dermatology

Introduction
Theoretical Considerations
Imaging of Epidermis
Imaging of Dermis
Discussion
List of Acronyms and Abbreviations
Glossary

Chapter 21. Noninvasive Topical In Vivo Imaging of Skin: Confocal Reflectance Microscopy and Polarized Light Imaging

Introduction
Confocal Reflectance
Polarized Light Imaging
Conclusion
Glossary

Chapter 22. Polarization Optical Imaging of Skin Pathology and Ageing

Introduction
Optical Interactions of Light With Skin
Reflectance Polarization Imaging of Human Skin
Fluorescence Polarization Imaging of Human Skin
Multimodal Imaging of Skin Cancers
Concluding Remarks

Chapter 23. Mechanical Characterization of Skin Using Surface Acoustic Waves

Introduction
Background and Characterization of Surface Acoustic Waves
Experimental Generation and Detection of Surface Acoustic Wave on In Vivo Human Skin
Signal Processing of Surface Acoustic Wave Phase Velocity Dispersion Curve
In Vivo Human Skin Elasticity Measurement by Surface Acoustic Wave Method
Conclusions

Chapter 24. Photoacoustic Tomography in the Diagnosis of Melanoma

Introduction
Major Embodiments of Photoacoustic Tomography for the Diagnosis of Melanoma
Photoacoustic Tomography in the Diagnosis of Melanoma
Further Potential Applications
Conclusions

Chapter 25. Ultrasound Imaging in Dermatology

Introduction
Technical Considerations
Normal Anatomy
Common Applications
Conclusion

Chapter 26. Optoacoustic Imaging of Skin

Introduction to the Optoacoustic (Photoacoustic) Technique
Optoacoustic Mesoscopy Systems for Skin Imaging
Skin Imaging With Broadband Raster-Scan Optoacoustic Mesoscopy
Discussion and Conclusion: Challenges and Perspectives of Raster-Scan Optoacoustic Mesoscopy
List of Acronyms and Abbreviations

Chapter 27. Use of Total Body Photography and Serial Digital Dermoscopy in Dermatology

Introduction
Total Body Photography
Serial (Sequential) Digital Dermoscopy
Total Body Photography With Serial Digital Dermoscopy
Conclusion

Chapter 28. Functional MRI Advances to Reveal the Hidden Networks Behind the Cerebral Processing of Itch

Introduction
Neurophysiological Aspects of Itch Transmission
A Brief Chronology of Brain Imaging Studies Dedicated to the Exploration of Itch Processing
Cerebral Areas Significantly Involved in Itch Processing
The Role of Brain's Reward Circuits in Itch Relief
Other Subcortical Centers Involved in Itch Processing
Brain Processing of Itch in Patients With Chronic Pruritus
Contagious Itch
Conclusions

Chapter 29. Magnetic Resonance Microscopy of Skin

Outline
Introduction
Status Quo for In Vivo Skin Magnetic Resonance Imaging on Humans
Low-Field Magnetic Resonance Imaging: First Steps Towards Clinical Routine
High-Field Magnetic Resonance Imaging: an Ex Vivo Approach
Conclusion
Glossary
List of Acronyms and Abbreviations

Chapter 30. The Role of Magnetic Resonance Imaging in the Management of Anogenital Hidradenitis Suppurativa

Introduction
Etiology
Pathogenesis
Clinical Manifestations
Diagnosis
Assessment of Disease Severity
Role of Imaging
Comparison With Other Imaging Modalities
Management
Conclusion

Chapter 31. Thermal Imaging in Dermatology

Introduction
Skin Thermal Properties
Fundamentals of Thermal Imaging
Applications in Dermatology
Conclusion
List of Acronyms and Abbreviations

Chapter 32. The Role of Positron Emission Tomography/Computed Tomography in Cutaneous Melanoma

Background
Staging Melanoma and the Role of Positron Emission Tomography/Computed Tomography
The Role of Positron Emission Tomography/Computed Tomography in Restaging
Positron Emission Tomography/Computed Tomography Technique
Comparison of Positron Emission Tomography/Computed Tomography With Other Imaging Modalities
Conclusion

Chapter 33. Molecular Imaging of Merkel Cell Carcinoma

Introduction
Molecular Imaging Methods
Conclusion

Chapter 34. Imaging in Merkel Cell Carcinoma

Introduction
Ultrasonography
Computed Tomography
Magnetic Resonance Imaging
Lymphoscintigraphy and Sentinel Lymph Node Biopsy
List of Acronyms and Abbreviations

Chapter 35. Imaging Evaluation of Cutaneous Lymphoma Using Functional and Structural Imaging

Introduction
Mycosis Fungoid and Sezary Syndrome
Nonmycosis Fungoides/Sezary Syndrome Cutaneous Malignant Lymphoma
Evaluating Tumor Biology and Behavior and Assessing Response to Treatment and Outcome
Quantification of Primary Cutaneous Lymphoma by 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Imaging Through a Global Approach
Conclusion

Chapter 36. Imaging Cutaneous Squamous Cell Carcinoma of the Head and Neck

Introduction
Clinical Presentation
Imaging of the Primary Lesion
Imaging for Regional and Distantly Metastatic Disease
Conclusion
List of Acronyms and Abbreviations
Glossary

Chapter 37. Imaging Patterns of Metastatic Melanoma

Introduction
Imaging Techniques
Metastatic Involvement of the Different Organ Systems
Conclusion
List of Acronyms and Abbreviations

Chapter 38. From Image to Information: Image Processing in Dermatology and Cutaneous Biology

Introduction
Purpose of Skin Image Processing
Motivation for Imaging in Dermatology
Trends in Skin Imaging and Image Processing
Progress in Skin Imaging Techniques
Skin Image Processing
Conclusions
Future Perspective
List of Acronyms and Abbreviations

Glossary
Index
Details

About the Editor

Michael R Hamblin Ph.D. is a Principal Investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital, an Associate Professor of Dermatology at Harvard Medical School and is a member of the affiliated faculty of the Harvard-MIT Division of Health Science and Technology. He was trained as a synthetic organic chemist and received his PhD from Trent University in England. His research interests lie in the areas of photodynamic therapy (PDT) for infections, cancer, and heart disease and in low-level light therapy (LLLT) for wound healing, arthritis, traumatic brain injury and hair-regrowth. He directs a laboratory of around a sixteen post-doctoral fellows, visiting scientists and graduate students. His research program is supported by NIH, CDMRP, USAFOSR and CIMIT among other funding agencies. He has published 252 peer-reviewed articles, over 150 conference proceedings, book chapters and International abstracts and holds 8 patents. He is Associate Editor for 7 journals, on the editorial board of a further 12 journals and serves on NIH Study Sections. For the past 9 years Dr Hamblin has chaired an annual conference at SPIE Photonics West entitled "Mechanisms for low level light therapy" and he has edited the 9 proceedings volumes together with four other major textbooks on PDT and photomedicine. He has several other book projects in progress at various stages of completion. In 2011 Dr Hamblin was honored by election as a Fellow of SPIE.

Harvard Medical School, Cambridge, MA, USA

Pinar Avci, MD is a Research Fellow in Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School Department of Dermatology, Boston USA. She received her MD degree in General Medicine from Semmelweis University, and is currently pursuing her PhD in Department of Dermatology, Venereology and Dermato-oncology, Semmelweis University, Budapest, Hungary. She is currently conducting research in the area of Photodynamic therapy (PDT) – a localized approach for treatment of cancer and infections and its effects in developing anti-tumor immunity.

Research Fellow, Department of Dermatology, Harvard Medical School, Cambridge, MA, USA

Gaurav Gupta did both his MBBS and MD at J.N. Medical College, Aligarh, India, and subsequently received PhD training at the Creighton University, Omaha, NE, USA and postdoctoral fellowship training at Massachusetts General Hospital, Harvard Medical School. Currently he is pursuing Residency training at Tufts Medical Center and a visiting postdoctoral fellow at Massachusetts General Hospital, Harvard Medical School.

Resident, Department of Pathology, Tufts University Medical Center, Boston, MA, USA

Imaging in Dermatology

Avci, P. — Hamblin, M. — Gupta, G.

ISBN 9780128028384

Editorial ACADEMIC PRESS

LIBRO IMPRESO

Table of Contents