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Osteoporosis, 2 Vols.
Marcus
1ª Edición Enero 2001
Inglés
910 pags
8000 gr
20 x 29 x 8 cm
ISBN 9780124708624
Editorial ACADEMIC PRESS
Osteoporosis
is a disease in which the amount of bone mass significantly decreases over a
period of time. Because of the decreased bone mass in patients with
osteoporosis, painful fractures occur, often caused by what would normally be
a mild trauma. Doctors are searching for a way to rectify this by identifying
treatments and therapies that can help prevent further bone loss and rebuild
the bone that has been depleted.
This Second Edition of the authoritative text in the field gives an objective
treatment of all relevant aspects of osteoporosis. Topics covered include
basic biology, anatomy, physiology, pathophysiology, preclinical issues,
experimental medicine, management, and therapeutics. Written by renowned
experts in this field, this book is a must-have for the researcher, the
academic clinician, or anyone in the field of bone biology.
Reviews
Praise for the
First Edition
"...interesting,
comprehensive and up-to-date: each chapter has something new and important to
say...Whichever direction one chooses to approach this monumental work I
predict it will be worthwhile"
-Journal of Bone
and Joint Surgery
"...a
textbook focused solely on this condition and encompassing this diversity of
research has been lacking. This book does a terrific job of filling the gap.
It contains 70 chapters grouped in six sections...All the chapters are
authoritative and include up-to-date references...Osteoporosis is quite
comprehensive; indeed, topics that typically receive brief treatment
elsewhere (osteoporosis in minority groups and in men) receive entire
chapters here...The book also covers relevant methodologic concepts, no doubt
reflecting the editors desire to make the material accessible to readers with
other primary research interests." -THE NEW ENGLAND JOURNAL OF MEDICINE
Features
- Approximately 30% new
material
- Each chapter has been
updated or revised
- Broad coverage of the
topic
- Well illustrated chapters
- Each chapter written by experts in their fields
Contents
Contributors
Preface
VOLUME 1 Part I Introduction to Normal Bone Physiology and
Pathophysiology
Chapter 1 The Bone Organ System: Form and Function
Cassandra A. Lee and Thomas A. Einhorn
Chapter 2 Osteoblast Biology
Jane B. Lian and Gary S. Stein
Chapter 3 Osteoclast Biology
F. Patrick Ross and Steven L. Teitelbaum
Chapter 4 The Biochemistry of Bone
Jayashree A. Gokhale, Pamela Gehron Robey, and Adele
L. Boskey
Chapter 5 Developmental Biology of Bone
Anthony M. Reginato, Wenfang Wang, and Bjorn R.
Olsen
Chapter 6 Mouse Genetics as a Tool to Study Bone
Development and Physiology
Millan S. Patel and Gerard Karsenty
Chapter 7 Parathyroid Hormone and Parathyroid
Hormone-Related Protein
Robert A. Nissenson
Chapter 8 Calcitonin
Ana O. Hoff, Gilbert J. Cote, and Robert F. Gagel
Chapter 9 Vitamin D: Biology, Action, and Clinical
Implication
David Feldman, Peter J. Malloy, and Coleman Gross
Chapter 10 Regulation of Bone Cell Function by
Estrogens
Barry S. Komm and Peter V. N. Bodine
Chapter 11 Skeletal Biology of Androgens
Kristine M. Wiren and Eric S. Orwoll
Chapter 12 Coupling of Bone Resorption and Formation
during Bone Remodeling
Thomas J. Martin and Gideon A. Rodan
Chapter 13 Cytokines and Bone Remodeling
Gregory R. Mundy, Babatunde Oyajobi, Kathy
Traianedes, Sarah Dallas, and Di Chen
Chapter 14 Bone Growth Factors
Xuezhong Qin, Reinhard Gysin, Subburaman Mohan, and
David J. Baylink
Chapter 15 Skeletal Heterogeneity and the Purposes
of Bone Remodeling: Implications for the Understanding of Osteoporosis
A. M. Parfitt
Chapter 16 Basic Biology of Bisphosphonates
H. Fleisch
Part II Structure and Biomechanics
Chapter 17 Skeletal Development: Mechanical
Consequences of Growth, Aging, and Disease
Marjolein C. H. van der Meulen, Dennis R. Carter,
and Gary S. Beaupr�
Chapter 18 Inhibition of Osteopenia by Biophysical
Intervention
Clinton T. Rubin and Kenneth J. McLeod
Chapter 19 Biomechanics of Age-Related Fractures
Mary L. Bouxsein
Part III Epidemiology and Risk Factors
Chapter 20 Introduction to Epidemiologic Methods
Jennifer L. Kelsey and MaryFran Sowers
Chapter 21 Magnitude and Impact of Osteoporosis and
Fractures
L. Joseph Melton III and Cyrus Cooper
Chapter 22 Race, Ethnicity, and Osteoporosis
Marie Luz Villa, Lorene Nelson, and Dorothy Nelson
Chapter 23 Epidemiology of Osteoporosis Fractures:
The European Experience
Chris de Laet and Jonathan Reeve
Chapter 24 Bone Mineral Acquisition in Utero ,
during Infancy, and throughout Childhood
Bonny Specker, Ran Namgung, and Reggie C. Tsang
Chapter 25 Bone Acquisition in Adolescence
Jean-Philippe Bonjour and Rene Rizzoli
Chapter 26 Genetics and Genomics of Osteoporosis
Andr� G. Uitterlinden, Johannes P. T. M. van
Leeuwen, and Huibert A. P. Pols
Chapter 27 Nutrition and Risk for Osteoporosis
Robert P. Heaney
Chapter 28 Physical Activity and Osteoporosis
Belinda R. Beck, Janet Shaw, and Christine M. Snow
Chapter 29 Premenopausal Reproduction and Hormonal
Characteristics and Risk for Osteoporosis
MaryFran Sowers
Chapter 30 Postmenopausal Endogenous and Exogenous
Hormones, Degree of Obesity, Thiazide Diuretics, and Risk of Osteoporosis
Jane A. Cauley and Loran M. Salamone
Chapter 31 The Effects of Tobacco and Alcohol Use on
Bone
Ego Seeman
Chapter 32 Falls as Risk Factors for Fractures
Anne Schwartz, Elizabeth Capezuti, and Jeane Ann
Grisso
Chapter 33 Assessing Fracture Risk
Charles W. Slemenda, C. Conrad Johnston, and Siu L.
Hui
Chapter 34 Outcomes of Osteoporotic Fractures
Elizabeth Barrett-Conner and Gail Greendale
VOLUME 2 Part IV Pathophysiology
Chapter 35 The Nature of Osteoporosis
Robert Marcus and Sharmilla Majumder
Chapter 36 Local and Systemic Factors in the
Pathogenesis of Osteoporosis
Lawrence R. Raisz
Chapter 37 Animal Models for in Vivo Experimentation
in Osteoporosis Research
Donald B. Kimmel
Chapter 38 The TypeI/Type II Model for Involutional
Osteoporosis: Update and Modification Based on New Observations
B. Lawrence Riggs, Sundeep Khosla, and L. Joseph
Melton III
Chapter 39 Bone Remodeling Findings in Osteoporosis
Robert R. Recker and M. Janet Barger-Lux
Chapter 40 The Role of Parathyroid Hormone and
Vitamin D in the Pathogenesis of Osteoporosis
John P. Bilezikian and Shonni J. Silverberg
Chapter 41 Postmenopausal Osteoporosis: How the Hormonal Changes of
Menopause Cause Bone Loss
Roberto Pacifici
Chapter 42 Osteoporosis
in Men: Epidemiology, Pathophysiology, and Clinical Characterization
Eric S. Orwoll and
Robert F. Klein
Chapter 43
Osteoporosis in Childhood and Adolescence
Laura K. Bachrach
Chapter 44
Glucocorticoid-Induced Osteoporosis: Basic Pathological Mechanisms, Clinical
Features, and Management in the New Millennium
Gary M. Leong,
Jacqueline R. Center, N. Kathryn Henderson, and John A. Eisman
Chapter 45
Familial Osteoporosis
Alan L. Burshell
and Steven R. Smith
Chapter 46
Immobilization Osteopenia
B. Jenny Kiratli
Chapter 47 Thyroid
Hormone and the Skeleton
Daniel Baran
Chapter 48
Osteoporosis in Gastrointestinal, Pancreatic, and Hepatic Diseases
Daniel D. Bikle
Chapter 49 Primary
Hyperparathyroidism and Hyperparathyroid Bone Disease
Lorraine A.
Fitzpatrick and Hunter Heath III
Chapter 50
Osteogenesis Imperfecta and Other Defects of Bone Development as Occasional
Causes of Adult Osteoporosis
Jay R. Shapiro
Chapter 51
Osteoporosis Secondary to Illnesses and Medications
Adina Schneider
and Elizabeth Shane
Chapter 52
Transplantation Osteoporosis
Sol Epstein and
Elizabeth Shane
Chapter 53
Osteoporosis Associated with Pregnancy
Lynn Kohlmeier and
Robert Marcus
Chapter 54
Osteoprosis Associated with Rheumatologic Disorders
Steven R. Goldring
Chapter 55 Oral
Bone Loss and Systemic Osteopenia
Marjorie K.
Jeffcoat, Michael S. Reddy, and Arthur A. Decarlo
Part V
Evaluation and Management
Chapter 56
Localized Osteoporosis
D. J. Schurman, W.
J. Maloney, and R. L. Smith
Chapter 57 The
Evaluation of the Patient with Osteoporosis or at Risk for Osteoporosis
Michael
Kleerekoper
Chapter 58 Imaging
of Osteoporosis
Michael Jergas and
Harry K. Genant
Chapter 59
Clinical Use of Bone Densitometry
Kenneth G.
Faulkner
Chapter 60
Biochemical Markers of Bone Turnover in Osteoporosis
P. Garnero and P.
D. Delmas
Chapter 61
Osteoporosis and Its Nonskeletal Consequences: Their Impact on Treatment
Decisions
Deborah T. Gold,
Kenneth W. Lyles, Kathy M. Shipp, and Marc K. Drezner
Chapter 62 An
Orthopedic Perspective of Osteoporosis
Michael H.
Heggeness and Kenneth B. Mathis
Chapter 63
Clinical Use of Bone Biopsy
P. Chavassieux, M.
Arlot, and P. J. Meunier
Part VI
Pharmacology and Therapeutics
Chapter 64 Design
Considerations for Clinical Investigations of Osteoporosis
Robert P. Heaney
Chapter 65
Development and Evaluation of New Drugs for Osteoporosis
Henry Bone
Chapter 66
Evidence-Based Decision Making in Osteoporosis
Ann B. Cranney and
Gordon H. Guyatt
Chapter 67 The
Role of Calcium in the Treatment of Osteoporosis
Bess Dawson-Hughes
Chapter 68 Vitamin
D and Its Metabolites in the Management of Osteoporosis
Ian R. Reid
Chapter 69
Estrogens and Osteoporosis
Robert Lindsay and
Felicia Cosman
Chapter 70
Selective Estrogen Receptor Modulators (SERMs)
Ethel S. Siris and
Douglas B. Muchmore
Chapter 71
Phytoestrogen and Other Phytochemical Effects on Bone
Richard Prince
Chapter 72
Bisphosphonates in the Management of Postmenopausal Osteoporosis
Socrates E.
Papapoulous
Chapter 73
Calcitonin
Roberto Civitelli
Chapter 74
Fluoride Therapy for Osteoporosis
K.-H. William Lau
and David J. Baylink
Chapter 75 A New
Perspective on Fluoride Therapy
Charles Y. C. Pak
Chapter 76
Androgens and Andogenic Progestins
Sundeep Khosla
Chapter 77
Treatment with PTH Peptides
Lis Mosekilde and
Jonathan Reeve
Chapter 78 Growth
Hormone and Insulin-Like Growth Factors: Potential Applications and
Limitations in the Management of Osteoporosis
Christian W�ster
and Clifford Rosen
Chapter 79 New
Approaches to Osteoporosis Therapeutics
S. Aubrey Stoch,
Michael Chorev, and Michael Rosenblatt
Index
© 2025 Axón Librería S.L.
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