The Prefrontal Cortex

Dedication
Preface
References

Chapter 1. Introduction

I Introduction

References

Chapter 2. Anatomy of the Prefrontal Cortex

I Introduction

II Evolution and Comparative Anatomy

III Development

IV Microscopic Architecture

V Aging

VI Connections

VII Summary

References

Chapter 3. Chemical Neurotransmission

I Introduction

II Development and Aging

III Transmitters in the Prefrontal Cortex

IV Neuropsychiatric Implications

V Summary

References

Chapter 4. Animal Neuropsychology

I Introduction

II Historical Background

III Motility

IV Emotional Behavior

V Cognitive Function

VI Reversible Lesions

VII Development

VIII Aging

IX Summary

References

Chapter 5. Human Neuropsychology

I Introduction

II Historical Background

III Affect, Emotion, and Social Behavior

IV Executive Function

V Language

VI Intelligence

VII Prefrontal Syndromes

VIII Development

IX Aging

X Summary

References

Chapter 6. Neurophysiology

I Introduction

II Historical Background

III Sensory Function

IV Motor Function

V Visceral and Emotional Functions

VI Value and Reward

VII Executive Functions

VIII Summary

References

Chapter 7. Neuroimaging

I Introduction

II Value and Limitations of Imaging

III Imaging Prefrontal Functions In Cognition

IV Prefrontal Imaging in Neuropsychiatric Illness

V Summary

References

Chapter 8. Overview of Prefrontal Functions: E Pluribus Unum – Coordinating New Sequences of Purposeful Action

I Conceptual Introduction

II Hierarchical Organization of Cognitive Networks (Cognits)

III Frontal Action Domains

IV Executive Functions

V Emotional Functions

VI Temporal Organization of Action

VII Prediction and Novelty in the Human Brain

VIII Consciousness and Free Will

IX Summary

References
Index

This is the completely revised and updated fourth edition of the undisputed classic on the prefrontal cortex. This area of the brain is the main executive center of cognitive function, and one of the seats of primate and human intelligence. This book is a unique exercise in analysis and synthesis of our knowledge on the subject, from a vast empirical foundation built by five generations of clinicians and neuroscientists. Previous editions of this text have guided the work of innumerable researchers worldwide; their findings are now in the substance of this new edition.