Progress in Molecular Biology and Translational Science, Vol. 114: G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis

Description

Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.

Table of Contents

1. G Protein-coupled receptors in energy homeostasis and obesity: An introduction
   Y. Tao
2. Ghrelin receptor in energy homeostasis and obesity pathogenesis
   W. Zhang
3. Obestatin receptor in energy homeostasis and obesity pathogenesis
   J. Zhang
4. Melanocortin-3 receptor in energy homeostasis and obesity pathogenesis
   A. Butler
5. Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis
   A. Hinney
   
   G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis
   H. Shi
6. Relaxin-3 receptor in energy homeostasis and obesity pathogenesis
   C. Liu
7. Cholecystokinin receptor in energy homeostasis and obesity pathogenesis
   A. Sayegh
8. Adiponectin receptor in energy homeostasis and obesity pathogenesis.
   B. Akingbemi