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Advanced Topics in Forensic DNA Typing: Methodology
Butler, J.
1ª Edición Julio 2011
Inglés
Tapa dura
704 pags
1600 gr
null x null x null cm
ISBN 9780123745132
Editorial ACADEMIC PRESS
DESCRIPTION
Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.
KEY FEATURES
- Contains the latest information - hot-topics and new technologies
- Well edited, attractively laid out, and makes productive use of its four-color format
- Author John Butler is ranked as the number one ''high-impact author in legal medicine and forensic science, 2001 to 2011'' by ScienceWatch.com
READERSHIP
Researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. Law enforcement, legal professionals, government/legal policy makers.
REVIEWS
"John Butler has produced a series of books detailing the major issues involved in forensic DNA typing. His latest book on advanced topics in DNA typing provides exceptional coverage of this complex and difficult topic. Through his work at NIST and his many collaborations with forensic analysts, Dr. Butler has kept up to date with all recent advances in the field. In his book he brings remarkable clarity through examples, diagrams, and case notes that is unsurpassed in any other text on the subject."
-- Bruce McCord, Professor, Department of Chemistry and Biochemistry, Florida International University, Miami, Florida
TABLE OF CONTENTS
- Sample Collection, Storage, and Characterization
- DNA Extraction Methods
- DNA Quantitation
- PCR Amplification: Capabilities and Cautions
- Short Tandem Repeat (STR) Loci and Kits
- Capillary Electrophoresis: Principles and Instrumentation
- Quality Assurance and Validation
- DNA Databases: Uses and Issues
- Missing Persons and Disaster Victim Identification Efforts
- Degraded DNA
- Low-Level DNA Testing: Issues, Concerns, and Solutions
- Single Nucleotide Polymorphisms and Applications
- Y-Chromosome DNA Testing
- Mitochondrial DNA Analysis
- X-Chromosome Analysis
- Non-Human DNA
- New Technologies and Automation
- Legal Aspects of DNA Testing and the Scientific Expert in Court
- Appendix 1 Reported Sizes and Sequences of STR Alleles
- Appendix 2 Familial DNA Searches: Potential, Pitfalls, and Privacy Concerns
- Appendix 3 List of Suppliers for DNA Instruments, Reagents, Services
- Appendix 4 Interviews Supporting Legal Aspects of DNA Testing
AUTHOR
By John M. Butler, Ph.D. (Analytical Chemistry), University of Virginia, National Institute of Standards and Technology (NIST), Gaithersburg, Maryland, USA
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