Movement Disorders

Overview

A comprehensive clinical reference on managing the entire spectrum of movement disorders

NEW DVD with video clips

Featuring contributions from more than one hundred leading experts, this full-color text covers pathophysiology, diagnosis, and management of all movement disorders - from ataxia to Parkinson's Disease. Movement Disorders examines the neurobehavioral changes and comorbidities that frequently occur and incorporates the latest genetic information and the most current references.

Chapters cover Clinical Presentation and Course, Pathophysiology, Differential Diagnosis, Etiologies, and Treatment. The third edition is highlighted by a new full-color presentation, more than 240 color illustrations and photos, and a DVD with video clips of patients with movement disorders.

Table of contents

• Contributors
• Foreword
• Preface

SECTION I: INTRODUCTION TO MOVEMENT DISORDERS

• 1. Overview of Movement Disorders and Approach to the Patient, Zbigniew K. Wszolek and Donald B. Calne
• 2. Assessing Disability in Movement Disorders: Quantitative Techniques and Rating Scales, Seth L. Pullman and Rachel Saunders-Pullman
• 3. Neuroimaging of Movement Disorders, David J. Brooks and Nicola Pavese

SECTION II: NEUROSCIENTIFIC FOUNDATIONS

• 4. Functional Anatomy of the Basal Ganglia, Yoland Smith
• 5. Pathophysiology of the Basal Ganglia and Movement Disorders, José A. Obeso, Maria c. Rodriguez-Oroz, Inés Trigo-Damas, and M. Rodriguez
• 6. Functional Neurochemistry of the Basal Ganglia, Anthony P. Nicholas and David G. Standaert
• 7. Neurotrophic Factors, Mart Saarma, Pivi Lindholm, and Urmas Arume
• 8. Neuropathology of Parkinsonian Syndrome, Dennis W. Dickson

SECTION III: CLINICAL DISORDERS

1. Parkinsonian States: Parkinson's Disease
• 9. Genetics of Parkinson's Disease and Parkinsonian Disorders, Andrew B. West
• 10. Epidemiology of Parkinson's Disease, Connie Marras and Caroline M. Tanner
• 11. Neurochemistry and Neuropharmacology of Parkinson's Disease, Federico Micheli, Maria G. Cersosimo, and G. Frederick Wooten
• 12. Etiology of Parkinson's Disease, Yoshikuni Mizuno, Nobutaka Hattori, and Hideki Mochizuki
• 13. Clinical Manifestations of Parkinson's Disease, Jayne R. Wilkinson, Daniel Weintraub, and Matthew B. Stern
• 14. Neuroprotective Therapies for Parkinson's Disease, Talene A. Yacoubian and David G. Standaert
• 15. Pharmacological Treatment of Parkinson's Disease, Werner Poewe and C. P. Mahlkne
• 16. Restorative Therapies for Parkinson's Disease, Olle Lindvall
• 17. Stereotaxic Surgery and Deep Brain Stimulation for Parkinson's Disease and Movement Disorders, Milind Deogonkar, Andre Machado, and Jerrold L. Vitek
• 18. Parkinson's Disease Dementia: Features and Management, Murat Emre, Hasmet A. Hanagasi, and David J. Burn
• 19. Parkinson's Disease: Neuropathology, John E. Duda
2. Other Parkinsonian Syndromes
• 20. Multiple-System Atrophy, Bradley J. Robottom, Lisa M. Shulman, and William J. Weiner
3. Parkinsonian States: Akinetic-Rigid Syndromes
• 21. Progressive Supranuclear Palsy, Lawrence J. Golbe
• 22. Corticobasal Degeneration, Natividad P. Stover and Ray L. Watts
• 23. Infectious, Postinfectious, Toxin-Induced, and Drug-Induced Parkinsonism, Rajesh Pabwa and Kelly E. Lyons
• 24. Rare Degenerative Syndromes Associated with Parkinsonism, Candan Depboylu, J. Carsten Müller, and Wolfgang H. Oertel
4. Tremor Disorders
• 25. Essential Tremor, Kelly E. Lyons
• 26. Uncommon Forms of Tremor, Shyamal H. Mehta, Kapil D. Sethi, and Bala V. Manyam
• 27. Pathophysiology of Tremor, Rodger J. Elble
• 28. Genetics Forms of Dystonia, Susan B. Bressman
• 29. Adult-Onset Idiopathic Focal Dystonias, Maria J. Marti and Eduardo S. Tolosa
• 30. Treatment of Dystonia, Octavian R. Adam and Joseph Jankovic
• 31. Symptomatic Dystonias, J.L. Lopez-Sendon, S. Cantarero, C. Tabernero, A.V. Vazquez, and J.G. de Yebenes
5. Choreatic Disorders: Huntington's Disease
• 32. Genetics and Molecular Biology of Huntington's Disease, James F. Gusella, Marcy E. Macdonald, and Vanessa C. Wheeler
• 33. Clinical Features and Treatment of Huntington's Disease, Sarah Wahlster and Jang-Ho J. Cha
• 34. Neuropathology and Pathophysiology of Huntington's Disease, Steven M. Hersch, H. Diana Rosas, and Robert J. Ferrante
• 35. Tardive Dyskinesia, Stacy Horn and Christopher G. Goetz
• 36. Other Choreatic Disorders, Margery H. Mark
6. Myoclonic Disorders
• 37. Classification, Clinical Features, and Treatment of Myoclonus, Rafael Gonzalez-Redondo, Asier Gomez, and Jose A. Obeso
• 38. Pathophysiology of Myoclonic Disorders, Camilo Toro and Mark Hallett
• 39. Tourette Syndrome and Related Disorders, Jorge L. Juncos
• 40. The Molecular Genetics of the Ataxias, George R. Wilmot, S.H. Subramony, and Henry L. Paulson
• 41. Physiology and Pathophysiology of the Cerebellum, and Rehabilitation Strategies After Cerebellar Injury, W. Thomas Thach
7. Other Movement Disorders
• 42. Wilson's Disease, Ronald F. Pfeiffer
• 43. Stiff-Person Syndrome, Oscar S. Gershanik
• 44. Gait Disorders, Lewis Sudarsky
8. Special Considerations
• 45. Movements Disorders in Childhood, Erika Augustine, Jonathan Mink, and Leon S. Dure
• 46. Restless Legs Syndrome and Periodic Leg Movement of Sleep, David B. Rye and Lynn Marie Trotti
• 47. Movement Disorders Specific to Sleep and Sleep in Waking Movement Disorders, Donald L. Bliwise, Lynn Marie Trotti, and David B. Rye
• 48. Psychogenic Movement Disorders, Daniel S. Sa, Nestor Galvez-Jimenez, and Anthony E. Lang
• 49. Systemic Illnesses that Cause Movement Disorders, Amy Colcher and Howard I. Hurtig

• Index

About the authors

Ray L. Watts, MD John N. Whitaker Professor and Chairman of Neurology Director of Clinical Research Parkinson's Disease and Movement Disorder Research Program University of Alabama at Birmingham
David G. Standaert, MD, PhD John and Juanelle Strain Professor of Neurology Director, Program for Neurodegeneration and Experimental Therapeutics Director, Movement Disorders Program Vice-Chair of Neurology University of Alabama at Birmingham
José A. Obeso, MD, PhD Consultant and Professor of Neurology Clinica Universitaria and Medical School Senior Researcher, Neuroscience, CIMA University of Navarra Pamplona, Spain