Medication Safety in Pregnancy and Breastfeeding. the Evidence-Based A-to-Z Clinician's Pocket Guide

OVERVIEW

An A-Z practical guide on the pharmacology and toxicology of pregnancy and nursing

Medication Safety in Pregnancy and Breastfeeding: The Evidence-Based, A-to-Z Clinician's Pocket Guide gives you comprehensive, authoritative coverage on the effects of prescription and over-the-counter drugs as well as herbals, chemicals, andradiologicals, on the mother, fetus, and nursing child. Organized A-Z for ease of use, this hands-on resource also includes evidence-based recommendations from the renowned Motherisk Program at the Hospital for Sick Children in Toronto.

ABOUT THE AUTHOR

Gideon Koren, MD is Director of the Motherisk Program at the Hospital for Sick Children, Toronto, Ontario, Canada, and Professor of Pediatrics, Pharmacology, Pharmacy, Medicine, and Medical Genetics at the University of Toronto, Canada. The author of over 800 peer-reviewed articles, abstracts, and books, including Nausea and Vomiting of Pregnancy: State of the Art 2000 (The Motherisk Program), he is a Diplomat of the American College of Medical Toxicology and the Royal College of Physicians and Surgeons of Canada, as well as a Senior Scientist of the Canadian Institutes of Health Research.

TABLE OF CONTENTS

Preface

Section I: Rules of Thumb for Taking Drugs During Pregnancy and Breastfeeding

• 1. Taking drugs during pregnancy: How safe are the unsafe? 
• 2. Which drugs are contraindicated during breastfeeding? Practice Guidelines 
• 3. Continuing drug therapy while breastfeeding: Common misconceptions of patients 
• 4. Continuing drug therapy while breastfeeding:  Common misconceptions of physicians 

Section II: Drug Safety A to Z 

• 5. Drug Safety -  A To Z 

Section III: Selected Drugs, Chemicals, and Medical Conditions: Frequently Asked Questions with Concise Evidence-based Answers 

• 6. Safe use of valproic acid during pregnancy 
• 7. Cancer chemotherapy during pregnancy: Consortium of cancer in pregnancy evidence 
• 8. Acetylsalicylic acid (ASA) and nonsteroidal anti-inflammatory drugs: (NSAIDS) during pregnancy 
• 9. Maternal obesity and risk of neural tube defects 
• 10. Antihistamines are safe during the first trimester 
• 11. Caffeine during pregnancy?: In Moderation 
• 12. Antimalarial drugs for rheumatoid disease during pregnancy 
• 13. Nicotine replacement therapy during pregnancy 
• 14. Safety of colchicines therapy during pregnancy 
• 15. Use of warfarin during pregnancy 
• 16. Can we use anxiolytics during pregnancy without anxiety? In moderation 
• 17. Nausea and vomiting of pregnancy: Evidence-based treatment algorithm 
• 18. Can herbal products be used safely during pregnancy? 
• 19. Taking ACE inhibitors during pregnancy: Is it safe? 
• 20. Prolonged exposure to angiotensin-converting enzyme inhibitors during pregnancy: Fetal toxicity could be reversible 
• 21. Low-molecular-weight heparins during pregnancy 
• 22. Drinking alcohol while breastfeeding: Will it harm my baby? 
• 23. Multivitamin supplements for pregnant women: New insights 
• 24. Folic acid and neural tube defects: Good news at last! 
• 25. Safety of gadolinium during pregnancy 
• 26. Taking ginger for nausea and vomiting during pregnancy 
• 27. Occupational exposure to inhaled anesthetic: Is it a concern for pregnant women? 
• 28. Using corticosteroids during pregnancy: Are topical, inhaled, or systemic agents associated with risk? 
• 29. Nonsteroidal anit-inflammatory drugs for rheumatoid arthritis during pregnancy 
• 30. Is topical tretinoin safe during the first trimester? 
• 31. How to ensure fetal safety when mothers use isotretinoin (Accutane) 
• 32. Young women taking isotretinoin still conceive: Role of physicians in preventing disaster 
• 33. Hypothyroidism during pregnancy 
• 34. Effects of prenatal exposure to marijuana 
• 35. Marijuana use and breastfeeding 
• 36. Metformin use during the first trimester of pregnancy: Is it safe? 
• 37. Is the fetus safe when spermicides fail? 
• 38. Acid-suppressing drugs during pregnancy 
• 39. Counseling pregnant women who are treated with paroxetine 
• 40. Discontinuing antidepressants and benzodiazepines upon becoming pregnant 
• 41. Risks of untreated depression during pregnancy 
• 42. Taking antidepressants during late pregnancy: How should we advise women? 
• 43. Taking St. John?s wort during pregnancy 
• 44. Trimethoprim-sulfonamide combination therapy in early pregnancy 
• 45. Influenza vaccination during pregnancy 
• 46. Antiretroviral treatment of maternal HIV infection