Molecular Biology

Description

Molecular Biology, 4/e by Robert Weaver, is designed for an introductory course in molecular biology. The text is geared not only toward presenting concepts of molecular biology, but also the experiments that led to those concepts. Guided by this experimental approach, Dr. Weaver has been published by National Institutes as well as National Geographic.

Key Features

Guide to Experimental Techniques
A summary guide to more than 75 experimental techniques, referenced to the pages on which the techniques are discussed, is found in the front matter.

Material from Original Publications
Significant data and autoradiographs from original publications are included to support the narrative and to help students analyze data.

Information on Affinity Chromatography
Chapter 5 (Molecular Tools for Studying Genes and Gene Activity) now includes information on Affinity Chromatography, one of the most powerful separation techniques, and also touches on Forensic Uses of DNA Fingerprinting and DNA Typing.

Table of Contents

Introduction
1 A Brief History
2 The Molecular Nature of Genes
3 An Introduction to Gene Function

Methods of Molecular Biology
4 Molecular Cloning Methods
5 Molecular Tools for Studying Genes and Gene Activity

Transcription in Prokaryotes
6 The Mechanism of Transcription in Prokaryotes
7 Operons: Fine Control of Prokaryotic Transcription
8 Major Shifts in Prokaryotic Transcription
9 DNA-Protein Interactions in Prokaryotes

Transcription in Eukaryotes
10 Eukaryotic RNA Polymerases and Their Promoters
11 General Transcription Factors in Eukaryotes
12 Transcription Activators in Eukaryotes
13 Chromatin Structure and Its Effects on Transcription

Posttranscriptional Events
14 Messenger RNA Processing I: Splicing
15 Messenger RNA Processing II: Capping and Polyadenylation
16 Other RNA Processing Events

Translation
17 The Mechanism of Translation I: Initiation
18 The Mechanism of Translation II: Elongation and Termination
19 Ribosomes and Transfer RNA

DNA Replication, Recombination, and Transposition
20 DNA Replication I: Basic Mechanism and Enzymology
21 DNA Replication II: Detailed Mechanism
22 Homologous Recombination
23 Transposition

Genomes
24 Genomics and Proteomics