Modern Keratoplasty. Surgical Techniques and Indications

Chapter 1: Introduction: current status of corneal transplantation: success, failures & turning points.- Part 1 - Preparing the Patient.- Chapter 2: Modern cornea eye banking: storage options, types of tissue .- Chapter 3: Risk classification and management of corneal grafts, Human Leukocyte Antigen matching, and options for immunosuppression therapy.- Chapter 4: Management of the vascularized cornea before corneal graft surgery - Fine needle diathermy - AntiVEGF.- Part 2 - Penetrating keratoplasty.- Chapter 5: Main issues to overcome in modern PK .- Chapter 6: Improvements in surgical techniques and suturing.- Chapter 7: Closing the wound: can sutures be avoided?.- Chapter 8: Femtosecond Assisted Penetrating Keratoplasty and Deep Anterior Lamelar Keratoplasty.- Chapter 9: Femtosecond Laser Assisted Tuck-In Penetrating Keratoplasty.- Chapter 10: Rescuing Failed Penetrating Keratoplasty Grafts.- Chapter 11: Excimer laser assisted PKP and DALK.- Part 3 - Epithelial Lamellar keratoplasty.- Chapter 12: Keratolimbal Grafts: outcomes, innovations and alternatives.- Chapter 13: Simple Limbal Epithelial Transplantation.- Chapter 14: Cultivated Limbal Epithelial Transplantation (CLET).- Chapter 15: Mesenchymal Stem Cells for Regeneration of the Ocular Surface.- Chapter 16: Induced pluripotent stem cells in epithelial lamellar keratoplasty.- Part 4 - Stromal Lamellar keratoplasty.- Chapter 17: Bowman layer transplantation.- Chapter 18: Anterior Lamellar Keratoplasty: current state of the art.- Chapter 19: Customised Lenticule addition keratoplasty (SLAK).- Chapter 20: Lamellar surgery with SMILE lenticles.- Chapter 21: Corneal Allogenic Intrastromal Ring Segments (CAIRS).- Chapter 22: Advanced DALK techniques: - Mushroom mini big bubble DALK.- Chapter 23: Large-Diameter Deep Anterior Lamellar Keratoplasty.- Chapter 24: Regenerative Surgery of the Corneal Stroma For Advanced Keraonus.- Part 5 - Endothelial Keratoplasty.- Chapter 25: Endothelial Keratoplasty. Historical review and current outcomes.- Chapter 26: Endothelial Keratoplasty: current state of the art .- Chapter 27: Corneal Endothelial Cell Transfer.- Chapter 28: Ultrathin DSAEK.- Chapter 29: Innovations in Descemet Membrane Endothelial Keratoplasty (DMEK).- Chapter 30: Descemet stripping only (DSO).- Chapter 31: Pre-Descemet's endothelial keratoplasty (PDEK) - Science and Surgery.- Chapter 32: Predescemetic endothelial keratoplasty (PDEK): clinical considerations and surgical details.- Chapter 33: DM transplant alone.- Chapter 34: Femtosecond Laser-Assisted Deep Lamellar Endothelial Keratoplasty.- Chapter 35: Femtosecond Descemet Membrane Endothelial Keratoplasty.- Chapter 36: Cultured cells for corneal endothelial therapy.- Chapter 37: What is new in Keratoprosthesis.- Chapter 38: Intraoperative OCT in Corneal Graft.- Chapter 39: Future Perspectives in corneal graft surgery.

Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells.

This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons.

Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.

Jorge L. Alio MD, PhD, FEBO
Universidad Miguel Hernandez, Vissum Miranza
Alicante, Spain C/ Cabañal, 1 03016 Alicante, SPAIN