Clinical and Diagnostic Virology

Preface
Acknowledgements
List of abbreviations
Introduction: basic virology
Section 1: Individual Viruses:
1. Adenoviruses
2. Arboviruses
3. Cytomegalovirus
4. Epstein-Barr virus
5. Enteroviruses
6. Hepatitis A virus
7. Hepatitis B and D viruses
8. Hepatitis C virus
9. Hepatitis E virus
10. Herpes simplex virus
11. HIV and AIDS
12. Human coronaviruses (including Covid-19, SARS and MERS)
13. Human herpesviruses types 6, 7 and 8
14. Human metapneumovirus
15. Human T-cell leukaemia viruses
16. Influenza viruses
17. Measles virus
18. Mumps virus
19. Noroviruses
20. Papilloma and polyoma viruses
21. Parainfluenza viruses
22. Parvovirus B19
23. Poxviruses
24. Rabies virus
25. Respiratory syncytial virus
26. Rhinoviruses
27. Rotaviruses
28. Rubella virus
29. Varicella-zoster virus
Section 2: Other Related Agents
30. Chlamydia
31. Toxoplasma gondii
32. Transmissible spongiform encephalopathies (CJD and vCJD)
Section 3: Clinical Syndromes
33. Atypical pneumonia
34. Central nervous system viral infections
35. Common cold
36. Genital tract and sexually transmitted infections
37. Glandular fever-type illness
38. Haemorrhagic fevers
39. Infections in pregnancy, congenital and neonatal infections
40. Respiratory virus infections
41. Travel-related infections
42. Viral eye infections
43. Viral gastroenteritis
44. Viral hepatitis
45. Virus infections in immunocompromised patients
46. Viral malignancies
47. Viral rashes
48. Viral zoonotic infections
Section 4: Laboratory Diagnosis
49. Sending specimens to the laboratory
50. Serological techniques
51. Virus detection: Molecular techniques
52. Virus detection: Non-molecular techniques
53. Quality control and laboratory accreditation
Section 5: Patient Management
54. Antiviral drugs
55. Viral vaccines
56. Infection control
57. Occupational health
58. Public health and pandemic preparedness
Index.

Since the first edition was published in 2009, there have been significant advances in diagnostics and management of viral infections, as well as newly discovered viruses such as SARS-CoV-2 and Zika virus. This new edition provides up-to-date information on the key developments in clinical and diagnostic virology, especially molecular diagnosis, with guidance on new molecular and bedside tests. Effective antiviral treatments and novel combinations of treatments recently introduced are covered in depth. Infection control precautions and pandemic preparedness are discussed, with a focus on recent outbreaks. As with the first edition, coverage is succinct and practical with easily accessible information in algorithms and tables, and standardised chapter layouts organised from A to Z. This is an ideal introduction to complex topics for healthcare trainees, as well as a handy and easily accessible reference for more experienced hospital clinicians and primary care physicians.

• Chapters are laid out in a standardised format, using algorithms and tables to present data, ensuring readers can quickly access the information they need
• Includes chapters on diagnostic techniques, quality control and laboratory accreditation, combining the theoretical side of viral diagnosis with the practical aspects and clinical utility of laboratory tests. Details of which specimens to take and how to interpret results make this an incredibly practical book
• Information is set out under individual virus chapters and then infections grouped under systemic syndromes, allowing the reader to access the information in multiple ways. Chapters are organised from A-Z to further increase accessibility
• Separate chapters cover vaccines, antivirals; occupational medicine, infection control and public health/pandemic preparedness. All chapters have embedded website for further reading, ensuring readers can view the most up to date information in this rapidly evolving field

Tim Wreghitt, Addenbrooke’s Hospital
Tim Wreghitt is a retired Consultant Clinical Scientist Virologist at Addenbrooke's Hospital, Cambridge, UK, and retired Associate Lecturer at Cambridge University. He has authored over 160 peer-reviewed scientific papers and co-authored four books. Dr Wreghitt has received several awards, including an OBE for services to clinical virology and NHS Healthcare Scientist of the Year.

Goura Kudesia, Sheffield Teaching Hospitals
Goura Kudesia is a retired Consultant Virologist at Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. She was also Honorary Senior Clinical Lecturer at the University of Sheffield and Honorary Professor of Clinical Virology at Sheffield Hallam University. Dr Kudesia has published over a hundred articles and presented at numerous national and international conferences.