The Massachusetts General Hospital Guide to Depression. New Treatment Insights and Options (Current Clinical Psychiatry)

Foreword-MGH Guide to Depression
Jerrold Rosenbaum

Foreword-Introduction and Historical Perspective
Maurizio Fava

Preface - Benjamin G. Shapero, David Mischoulon, Cristina Cusin

Part 1 Severe and Comorbid Conditions

Chapter 1 Treatment-Resistant Depression
Cristina Cusin and Stefan Peyda

Chapter 2 Co-Occurring MDD and Problematic Alcohol Use
Paola Pedrelli and Kate H. Bentley

Part 2 Special Population Considerations

Chapter 3 Depression and Chronic Medical Illness: New Treatment Approaches
Trina E. Chang and Sean D. Boyden

Chapter 4 Culture and Depression: Clinical Considerations for Racial and Ethnic Minorities
Nhi-Ha Trinh and Taquesha Dean

Chapter 5 Early Onset of Depression During Childhood and Adolescence
Benjamin G. Shapero and Erica Mazzone

Chapter 6 Cross-Cultural Approaches to Mental Health Challenges Among Students
Xiaoqiao Zhang, Tat Shing Yeung, Yi Yang, Rohit M. Chandra, Cindy H. Liu, Dana Wang, Sukhmani K. Bal, Yun Zhu, Rebecca Nika W. Tsai, Zhenyu Zhang, Lusha Liu and Justin A. Chen

Chapter 7 Depression After Traumatic Brain Injury
Lauren B. Fisher, Garrett Thomas, Ryan A. Mace, and Ross Zafonte

Part 3 Medication Approaches

Chapter 8 Personalized Medicine
Simmie L. Foster, Samuel R. Petrie, David Mischoulon, and Maurizio Fava

Chapter 9 Depression, Antidepressants, and Sexual Functioning
Christina M. Dording and Sean D. Boyden

Chapter 10 Ketamine as a Rapid Antidepressant
Cristina Cusin

Chapter 11 Neuroactive Steroids and Depression
Karen K. Miller

Part 4 Psychotherapy Approaches

Chapter 12 Unified Protocol for Treatment of Depression
Kate H. Bentley, Laren R. Conklin, James F. Boswell, Benjamin G. Shapero, and Olenka S. Olesnycky

Chapter 13 Mindfulness Based Cognitive Therapy
Benjamin G. Shapero, Jonathan Greenberg, Paola Pedrelli, Gaelle Desbordes, and Sara W. Lazar

Chapter 14 The Role of Technology in the Treatment of Depression
Paola Pedrelli, Kate H. Bentley, Esther Howe, and Benjamin G. Shapero

Part 5 Alternative Treatment Approaches

Chapter 15 Supplements and Natural Remedies for Depression
David Mischoulon and Nadia Iovieno

Chapter 16 The Effects of Tai Chi and Qigong on Anxiety and Depression
Albert Yeung, Benjamin Campbell, and Jessie S. M. Chan

Chapter 17 Yoga as a Treatment for Depression
Maren Nyer, Regina Roberg, Maya Nauphal, and Chris Streeter

Chapter 18 Photobiomodulation
Marco Antonio Caldieraro and Paolo Cassano

Major Depressive Disorder (MDD) is one of the most prevalent psychiatric disorders, with a lifetime prevalence rate of roughly 20%. MDD is a leading cause of disability and premature death worldwide, leads to greater impairment in work functioning than other chronic medical conditions, and has an estimated annual cost of $210 billion in the US.

The proposed text is designed for mental health professionals and will present state-of-the-art treatment options that are used in the Depression Clinical and Research Program (DCRP) at the Massachusetts General Hospital. The text provides different treatment options so that providers can `think outside the box' of conventional interventions. The introductory sections discuss general themes about diagnosing and treating depression. The major body of the book, however, consists of chapters organized under the topics of new medication, new psychotherapy, alternative treatments, and consideration of specific populations and how to modify interventions to best treat these patients. Each chapter begins with a case vignette to illustrate key characteristics of the disorder process or treatment and reviews the history, research support, and new advances of these topics. In addition, the chapters include a description of how to apply this topic in treatment and frequently asked questions and answers.

This book will be a unique contribution to the field. Existing guides focus on individual treatments of Depression, or include brief descriptions of interventions as a whole. The DCRP has consistently been a forerunner of clinical treatments for depression and often treats challenging cases of this disorder. This book will provide a practical and useful resource with wide applicability.