Prostate Biopsy Interpretation. An Illustrated Guide

Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Interpretation.- Needle Biopsy Sampling Techniques and Role of Multiparametric-Magnetic Resonance Imaging Modality in Prostate Cancer Diagnosis and Management.- Diagnosis of Limited Cancer in Prostate Biopsy.- Immunohistochemistry in Prostate Biopsy Evaluation.- Contemporary Approach to Gleason Grading of Prostate Cancer.- Histologic Variants of Acinar Adenocarcinoma, Ductal Adenocarcinoma, Neuroendocrine Tumors, and Other Carcinomas.- Benign Mimics of Prostate Carcinoma.- Intraductal Carcinoma of the Prostate (IDC-P) and Atypical Intraductal Proliferation (AIP).- High-Grade Prostatic Intraepithelial Neoplasia.- Atypical Glands Suspicious for Cancer.- Spindle Cell Lesions of the Prostate Gland.- Treatment Effect in Benign and Malignant Prostate Tissue.- Molecular Biology of Prostate Cancer and Role of Genomic Testing in Diagnosis and Prognosis of Prostate Cancer.- Biopsy Specimen Handling, Processing, and Quality Assurance Program.- Reporting of Prostate Biopsy.- Pattern-based approach to Prostate Biopsy Interpretation.

This book retains the core contents of the successful first edition and covers all the practical issues related to prostate biopsy diagnosis in day-to-day practice. It uses abundant algorithms, flow charts, and tables to simulate a pathologist's thought process and assist decision making during evaluation of prostate biopsies. Chapters address the most effective ways to evaluate a prostate biopsy and how to formulate a diagnostic approach upon encountering a specific clinical problem. Pertinent new information is incorporated in all chapters, particularly in how novel diagnostic tools such as MRI and genomic tests may affect prostate biopsy practice and diagnosis. An entirely new chapter on pattern-based approaches to prostate biopsy interpretation has been added.

The second edition of Prostate Biopsy Interpretation: An Illustrated Guide is not meant to be an all-encompassing, definitive bibliography of pathology of prostate cancer. Instead, it provides practicing surgical pathologists and trainees a quick and handy reference for all the practical issues relevant to day-to-day interpretation of prostate biopsy.

Rajal B. ShahThe Cleveland ClinicCleveland, OH USA Ming Zhou The University of Texas Southwestern Medical CenterDallas, TX USA