Clinical Investigation of Portal Hypertension

Part 1 Pathology of portal hypertension 1. Pathology of liver cirrhosis in Japan2. Pathological findings for esophageal varices3. Anatomy of the spleen and pathology of hypersplenism4. Pathology of non-cirrhotic liver disease

Part 2 Clinical pathophysiology and diagnosis of portal hypertension5. Mechanism and pathophysiology of portal hypertension6. Mechanism and pathophysiology of bleeding from esophagogastric varices7. Endoscopic diagnosis of esophagogastric varices8. Diagnosis and hemodynamics of ectopic varices9. The role of endoscopic ultrasonography for esophagogastric varices10. Contrast-enhanced ultrasound of the liver cirrhosis11. Liver and spleen stiffness measurement12. Portal vein hemodynamics: 3DCT 13. Portal vein hemodynamics: MR imaging, MR angiography 14. Endoscopic varicealography during endoscopic injection sclerotherapy (EVIS)15. Angiographic evaluation of portal hypertension16. The Baveno VI workshop: European consensus meeting on portal hypertension, and comparison with Japanese guidelines

Part 3 Complications of portal hypertension: Gastrointestinal varices17. Conservative treatment : Pharmacological therapy18. Conservative treatment : Balloon tamponade19. Conservative treatment : Nutritional treatment 20. Endoscopic treatment of esophageal varices: Selection of treatment method21. Endoscopic treatment of esophageal varices: Obara method 22. Endoscopic treatment of esophageal varices: Kitano method23. Endoscopic treatment of esophageal varices: Takase method24. Endoscopic treatment of esophageal varices: Suzuki method25. Endoscopic treatment of esophageal varices: Consolidation method following Ethanolamine oleate/Aethoxysclerol combination therapy26. Endoscopic treatment of esophageal varices: Eradicative endoscopic variceal ligation27. Endoscopic treatment of esophageal varices: bimonthly endoscopic variceal ligation 28. Endoscopic treatment of esophageal varices: Endoscopic variceal ligation using a multi-band ligator29. Endoscopic treatment of esophageal varices: Simultaneous combination of endoscopic injection sclerotherapy and endoscopic variceal ligation30. Endoscopic treatment of esophageal varices: Combination of endoscopic variceal ligation and endoscopic Injection sclerotherapy31. Endoscopic treatment of esophageal varices: Endoscopic variceal ligation followed by argon plasma coagulation32. Endoscopic treatment of esophageal varices: Simultaneous combination of endoscopic injection sclerotherapy and endoscopic variceal ligation for prevention of recurrence33. Choice of therapy for gastric variceal bleeding: Results from a cohort study in Japan34. Endoscopic treatment of gastric varices: Histoacryl method35. Endoscopic treatment of gastric varices: -cyanoacrylate monomer method 36. Endoscopic treatment of gastric varices: Indwelling snare method37. Hemodynamics and treatment of ectopic varices38. Interventional radiology: Balloon-occluded retrograde transvenous obliteration39. Interventional radiology: Transjugular retrograde obliteration 40. Interventional radiology: Percutaneous transhepatic obliteration and transileocolic obliteration41. Interventional radiology : Ttransjugular intrahepatic portosystemic shunt42. Interventional radiology : Partial splenic embolization43. Surgical treatment: Sugiura procedure and Hassab's operation44. Surgical treatment: Selective shunt surgery45. Surgical treatment:Laparoscopic splenectomy

Part 4 Complications of portal hypertension: Portal hypertensive gastroenteropathy46. Diagnosis and endoscopic classification of portal hypertensive gastroenteropathy47. Treatment of portal hypertensive gastroenteropathy

Part 5 Complications of portal hypertension: Portal vein thrombosis48. Diagnosis of Portal vein thrombosis49. Treatment of the portal vein thrombosis

Part 6 Complications of portal hypertension: Refractory ascites50. Diagnosis of refractory ascites51. Treatment of refractory ascites

Part 7 Complications of portal hypertension: Spontaneous bacterial peritonitis 52. Diagnosis of spontaneous bacterial peritonitis 53. Treatment of spontaneous bacterial peritonitis

Part 8 Complications of portal hypertension:Hepatic encephalopathy54. Diagnosis of hepatic encephalopathy55. Treatment of hepatic encephalopathy56. [Column] Portosystemic shuntopathy: This column is the postscript to Chapter 5

Part 9 Aberrant portal hemodynamics57. Idiopathic Portal Hypertension58. Budd-Chiari syndrome 59. Extrahepatic Portal Obstruction

Part 10 Portal hypertension and liver transplantation60. Portal hypertension and liver transplantation: Current situation in Japan and overseas

Part 11 Future prospects on portal hypertension61. Future prospects in the treatment of portal hypertension

This book thoroughly covers various diseases induced by portal hypertension, and introduces novel information for the treatment of patients. Individual chapters address the pathophysiology, diagnosis and treatment options available for the complications induced by portal hypertension. The book fosters practical understanding and provides more evidence-based treatment options in order to improve physicians' ability to select optimal treatment methods for their patients. Further, it offers readers the latest information concerning developments of the disease such as esophaogastric varices, ectopic varices, portal thrombosis, refractory ascites and hepatic encephalopathy.

Clinical Science of Portal Hypertensions is an indispensible resource for both beginning and experienced gastroenterological physicians, endoscopists, liver physicians, radiologists, gastroenterological surgeons, liver surgeons, etc. who treat patients with portal hypertension on a clinical or research basis.

Katsutoshi Obara. Department of Advanced Gastrointestinal Endoscopy. Fukushima Medical University. Fukushima, Japan