An Introduction to Medicinal Chemistry

medicinal chemistry

1. Drugs and Drug Targets
2. Protein Structure and Function
3. Enzymes: Structure and Function
4. Receptors: Structure and Function
5. Receptors and Signal Transduction
6. Nucleic Acids: Structure and Function
7. Enzymes as Drug Targets
8. Receptors as Drug Targets
9. Nucleic Acids as Drug Targets
10. Miscellaneous Drug Targets
11. Pharmacokinetics and Related Topics Chapter Case Study 1 Statins
12. Drug Discovery: Finding a Lead
13. Drug Design: Optimizing Target Interactions
14. Drug Design: Optimizing Access to the Target
15. Getting the Drug to Market

An Introduction to Medicinal Chemistry, Seventh Edition, offers a complete and accessible approach to this multidisciplinary field. Its student-friendly writing style makes this text an ideal tool for those coming to the subject for first time, but also for students looking to deepen their understanding. From principles to practice, accompanied by examples and case studies emerging from current biomedical research, this book will equip students with a robust understanding of medicinal chemistry and prepare them for future success.

The author's renowned clarity of writing and the book's logical structure help to address the challenges of teaching and studying Medicinal Chemistry
New chapters on Protein Kinase and Antibodies provide insightful, up-to-date coverage of some of the most significant topics in the subject today
The pedagogical features enhance student engagement, which supports better knowledge retention and a more confident application of concepts and ideas to unfamiliar problems
Boxes and case studies support a real-life applied approach that helps lecturers to show how theoretical content relates to the practical reality of medicinal chemistry
Full-color images throughout the new edition enhance the student experience by helping them to better visualize the concepts presented
New and updated exercises, questions, and activities throughout the book and online help students to hone their problem-solving skills
Also available as an e-Book with functionality, navigation features, and links that offer extra learning support

New to this Edition:

Newly added high-level Multiple-Choice Questions to support self-directed learning and challenge the understanding of the processes and concepts covered
Updated and new Protein Data Bank Exercises available online
New and updated assignments to help students develop their data analysis and problem-solving skills
Full-color images throughout the new edition enhance the student experience by helping them to better visualize the concepts presented
Also available as an e-Book with functionality, navigation features, and links that offer extra learning support

Graham Patrick, Lecturer in Organic Chemistry and Medicinal Chemistry, University of the West of Scotland

Dr. Graham Patrick gained his BSc Honours at Glasgow University, winning the McKay-Smith Prize for Chemistry. He completed his PhD with Professor Kirby and Professor Robins, studying the biosynthesis of gliotoxin and related fungal metabolites. Following this, he worked in the pharmaceutical industry as a research chemist and radiochemist on a variety of projects that included such topic areas as opioids, antibacterial agents, and antidepressants. His academic career has included positions at Leeds and Strathclyde Universities as well as the Australian National University. He joined the University of Paisley (now the University of the West of Scotland) in 1990, teaching medicinal chemistry and drug design. Currently, he is an Associate Lecturer with the Open University, an author of scientific textbooks and fiction, and a historical archivist.

An Introduction to Medicinal Chemistry

Patrick, G.

ISBN 9780198866664

Publisher OXFORD

Printed Book