The ESC Textbook of Cardiovascular Development

1: Relevance of developmental studies for clinicians, Cristina Basso, Deborah Henderson, José Luis de la Pompa, Robert G. Kelly, José Maria Pérez-Pomares, David Sedmera, & Maurice van den Hoff
Section 1: Origin, distribution and determination of cardiovascular cell progenitors
2: An evolutionary perspective on the origin of the cardiovascular system of vertebrates, A.F. Moorman, Bjarke Jensen, & R.J. Oostra
3: From epiblast to mesoderm: elaboration of a fate map for cardiovascular progenitors, Carmen Lopez-Sanchez, Virginio Garcia-Lopez, Gary C. Schoenwolf, & Virginio Garcia-Martinez
4: Cardiac Fields and myocardial cell lineages, Christopher De Bono & Robert G. Kelly
5: Origin and diversity of embryonic endothelium/endocardium, LeShana SaintJean & H.S. Baldwin
6: Transcriptional regulation of early cardiovascular development, F. Gabriella Fulcoli and Antonio Baldini
Section 2: Molecular regulation of cardiac tissue differentiation and patterning
7: Incorporation of myocardial progenitors to the arterial pole of the heart, Mayyasa Rammah, Francesca Rochais, & Robert G. Kelly
8: The Developmental Origin of Myocardium at the Venous Pole of the Heart, Bram van Wijk, Phil Barnett & Maurice J B van den Hoff
9: Cardiac growth (I): Cardiomyocyte proliferation, Sigolène M. Meilhac
10: Cardiac growth (I): Cardiomyocyte polarisation, Stéphane Zaffran
11: Defining cardiac domains from the inside: NOTCH in endocardial-myocardial interactions, Gaetano D'Amato, Guillermo Luxán & José Luis de la Pompa
12: Origin and diversity of cardiac fibroblasts: developmental substrates of adult cardiac fibrosis, Adrián Ruiz-Villalba, Nikolaos Frangogiannis, & José Maria Pérez-Pomares
Section 3: Morphogenesis of cardiovascular structures. On form and function
13: Building the cardiovascular system: the acquisition of a functional form, David Sedmera & Robert P. Thompson
14: Cardiac looping and laterality, Marina Campione, Amelia Aranega & Diego Franco
15: Origin and development of the cardiac conduction system, Lucile Miquerol
16: Blood vessel differentiation and growth, Rui Benedito and Arndt Friedrich Siekmann
17: From cushions to leaflets: Morphogenesis of cardiac atrioventricular valves, D MacGrogan, Jose Maria Pérez-Pomares, Bill Chaudhry, Jose-Luis de la Pompa and Deborah Henderson
18: Development of the arterial valves, Deborah J. Henderson, Bill Chaudhry, and José Luis de la Pompa
19: The role of neural crest in cardiac development, Laura A. Dyer & Margaret L. Kirby
20: The multiple functions of the proepicardial/epicardial cell lineage in heart development, Robert Dettman, Juan Antonio Guadix, Elena Cano, Rita Carmona, & Ramón Muñoz-Chápuli
21: The development of coronary vascularization, Robert J. Tomanek, Adriana A. Silva Pires Gomes, José Maria Pérez-Pomares
Section 4: Abnormal cardiac morphogenesis and the origin of congenital heart disease
22: The genetics of congenital heart disease, Jamie Bentham
23: Development of the Outflow Tract, Robert H. Anderson, Nigel A. Brown, Simon D. Bamforth, Bill Chaudhry, Deborah J. Henderson, and Timothy J. Mohun
24: Arterial wall remodelling in congenital heart disease, S. Yen Ho and Matina Prapa
25: Coronary anomalies, Cristina Basso, José Maria Perèz-Pomares, Gaetano Thiene, and Lucile Houyel
26: Myocardial non-compaction, Mary Sheppard
27: Developmental Aspects of Cardiac Arrhythmias, Alex V. Postma, David Sedmera, Frantisek Vostarek, Vincent M. Christoffels, and Connie R. Bezzina
Section 5: Frontiers in cardiovascular development
28: Advanced therapies to treat cardiovascular diseases. Controversies and perspectives, Mauro Giacca and Borja Ibáñez
29: The zebrafish as a model for cardiac development and regenerationPerivascular adipose tissue and metabolic syndrome, Bill Chaudhry, José Luis de la Pompa, and Nadia Mercade
30: Cells to repair the infarcted myocardium, Daniela Salvatori, Harsha.D. Devalla and Robert Passier
31: The role of non-coding RNA/micro RNAs in cardiac disease, Yolan J. Reckman and Yigal M. Pinto
32: Egigenetics and post-transcriptional regulation of cardiovascular development, Jin Yang, Pei Han, Wei Li, and Ching-Pin Chang
33: Complex network interactions: cardiovascular system biology, Marcel Grunert, Andreas Perrot, and Silke Rickert-Sperling

• Contains over 70 full-colour illustrations throughout to aid understanding
• Prepared by the Working Group on Development, Anatomy and Pathology of the ESC
• Modern concepts pivotal to the understanding of cardiovascular morphogenesis highlighted
• Linked to the ESC Core Curriculum

This highly illustrated textbook has been prepared by the Working Group on Development, Anatomy and Pathology of the European Society of Cardiology (ESC). The ESC Textbook of Cardiovascular Development is the authority on cardiovascular development from a perspective of both basic scientists and clinicians. 

The embryonic origin of congenital heart diseases and their pathology has been analysed in depth. Modern concepts pivotal to the understanding of cardiovascular morphogenesis, including those still subject to controversy, have been highlighted and the content covers the ESC Core Curriculum. 

The textbook will appeal to researchers and clinicians from a wide spectrum of disciplines including molecular and developmental biologists working on mechanisms of heart development in a range of model organisms as well as pathologists, morphologists, geneticists, and cardiologists.