NELSON's Neonatal Antimicrobial Therapy

Introduction
1. Choosing an Antibiotic for the Neonate
2. Antimicrobial Drug Therapy for Neonates
A. Neonatal Pharmacokinetics
B. Antimicrobial Pharmacodynamics
C. Drug Dosage Tables
D. Therapeutic Drug Monitoring
E. Individual Drug Monographs
..... Acyclovir
..... Amphotericin B
..... Ampicillin
..... Cefazolin
..... Cefepime
..... Cefotaxime
..... Ceftazidime
..... Fluconazole
..... Gentamicin
..... Meropenem
..... Micafungin
..... Nafcillin/Oxacillin
..... Penicillin G
..... Piperacillin-Tazobactam
..... Vancomycin
3. Bacterial Infections in Neonates
Conjunctivitis
Gastrointestinal infections
Osteomyelitis, suppurative arthritis
Otitis media
Parotitis, suppurative
Pulmonary infections
Sepsis and meningitis
Skin and soft tissues
Syphilis, congenital (<1 mo of age)
Syphilis, congenital (>1 mo of age)
Tetanus neonatorum
Tuberculosis
Urinary tract infection
4. Viral Infections in Neonates
Cytomegalovirus
Enterovirus
Hepatitis B
Hepatitis C
Herpes simplex virus infection (HSV-1 and HSV-2)
Human immunodeficiency virus
Influenza A and B viruses
Respiratory syncytial virus
Varicella-zoster virus
5. Fungal Infections in Neonates
Aspergillosis
Candida spp
Malassezia spp
Mucormycosi
Pneumocystis jiroveci pneumonia
6. Parasitic Infections in Neonates
Amebiasis
Babesiosis
Chagas disease
Cryptosporidium
Giardiasis
Malaria
Scabies
Toxoplasmosis, congenital
7. Antimicrobial Stewardship in the Nursery
Index

Completely updated and revised, Nelson’s Neonatal Antimicrobial Therapy, Second Edition, provides the most current, practical, and evidence-based recommendations for health care professionals treating neonates. Developed by leading experts in antimicrobial therapy, this resource aims to help clinicians select the right drug, dose, and duration for the treatment of bacterial, viral, fungal, and parasitic infections in neonates.

Neonatal infectious disease therapeutics research continues to expand and respond to emerging novel pathogens and bacterial resistance. The recommendations in this book are based on the best available evidence to provide those taking care of neonates with the best possible treatment decisions, with updated guidance on dosing for low-birth-weight newborns, drug monographs for commonly prescribed drugs, and antimicrobial stewardship guidance for the nursery.

Joseph B. Cantey, MD, is an Associate Professor of Pediatrics in the Divisions of Pediatric Infectious Diseases and Neonatology/Perinatal Medicine at the University of Texas Health Science Center in San Antonio. He attended medical school at the Medical University of South Carolina before completing his pediatric residency at Johns Hopkins. He then completed dual fellowships in pediatric infectious diseases and neonatal/perinatal medicine at the University of Texas Southwestern in Dallas, Texas. His research interests include antimicrobial stewardship and responsible prescribing in the nursery setting; infection control and prevention in the nursery setting; and the pathogenesis, diagnosis, treatment, and longitudinal follow-up of congenital and perinatal infections, particularly herpes simplex virus, cytomegalovirus, and syphilis.

Jason Sauberan, PharmD, is Assistant Clinical Professor at the University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences and a pediatric consultant pharmacist at the Helen Bernardy Center for Medically Fragile Children, Rady Children’s Hospital San Diego. His research interests include anti-infection therapy, drugs in breast milk, parenteral nutrition, and medication safety. He serves on the Scientific Advisory Board of Mother to Baby California, and is an assistant clinical professor, UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences.

John D. Nelson, MD is Professor Emeritus of Pediatrics at the University of Texas Southwestern Medical Center and Children's Medical Center, the same institution since he started his career back in 1957. At UT Southwestern he established the first formal Pediatric Infectious Disease fellowship program with Dr. Kenneth Haltalin and later Dr. George McCracken. He also went on to establish the National Pediatric Infectious Disease Seminar with Dr. McCracken and in 1982 they founded the Pediatric Infectious Disease Journal for which they continue as Chief Editors. In 1975 Dr. Nelson produced the first edition of the Pocket Book of Pediatric Antimicrobial Therapy which has gone through 20 biennial editions and is now edited by Dr. John Bradley.