Haematology in Critical Care. a Practical Handbook

Description

Issues of thrombosis, bleeding, and transfusion are extremely common, and often complex, in critically ill patients.

Haematology in Critical Care: A Practical Handbookprovidesa dependable source of expert guidance on how to handle common haematological problems seen in the critical care setting, as well as the acute care of patients with a primary haematological disorder.

Full-time clinical haematologists, regularly attending on intensive care, the Editors begin with an approach to abnormal laboratory tests, following with a disease-orientated approach to topics such as coagulation and haematological malignancy. Other key topics include paediatric and neonatal care, transfusion, point of care testing and the emergency presentation of haematological disease.

This title brings together two of the most highly scientific specialties in clinical practice, delivering a practical approach to these problems, and guiding the clinician through the diagnosis and management of common scenarios encountered in the ICU.

Table of Contents

List of Contributors
Preface
Acknowledgements

Section 1 Approach to Abnormal Blood Tests

• 1 Diagnostic Approach to Anaemia in Critical Care, 3
  Stephen F. Hawkins and Quentin A. Hill
• 2 Leukopenia, 9
  Stephen F. Hawkins, Jecko Thachil and Quentin A. Hill
• 3 Thrombocytopenia in the Intensive Care Unit, 12
  Jecko Thachil
• 4 High Blood Counts, 16
  Quentin A. Hill
• 5 The Abnormal Clotting Profile, 26
  Jecko Thachil
• 6 Understanding the Blood Film, 31
  Stephen F. Hawkins and Quentin A. Hill

Section 2 Approach to Coagulation Problems

• 7 Venous Thromboembolism in Intensive Care, 39
  Sarah A. Bennett and Roopen Arya
• 8 Reversal and Monitoring of Anticoagulants, 45
  Joost J. van Veen
• 9 Disseminated Intravascular Coagulation, 52
  Jecko Thachil
• 10 Heparin-Induced Thrombocytopenia, 58
  Jerrold H. Levy and Anne M. Winkler
• 11 Thrombotic Microangiopathies, 62
  Mari Thomas and Marie Scully
• 12 Critical Care of Patients with a Congenital Bleeding Disorder, 69
  Vanessa Martlew

Section 3 Approach to Transfusion Problems

• 13 Blood Components and Their Contents, 77
  Shubha Allard
• 14 Transfusion Reactions, 86
  Therese A. Callaghan
• 15 The Management of Non-traumatic Massive Haemorrhage, 93
  Nicola S. Curry and Simon J. Stanworth
• 16 Plasma Exchange, 100
  Khaled El-Ghariani

Section 4 Approach to Red Cell Problems

• 17 Appropriate Haemoglobin in Intensive Care, 107
  Jonathan Wallis and Stephen Wright
• 18 Sickle Cell Disease and Thalassaemia in the Critical Care Setting, 112
  Andrew Retter and Jo Howard
• 19 Management of Patients Who Refuse Blood Transfusion, 118
  Derek R. Norfolk and Fran Hartley

Section 5 Approach to White Cell Problems

• 20 Infectious Complications in the Immunosuppressed Patient, 125
  Tim Collyns and Elankumaran Paramasivam
• 21 Haematopoietic Stem Cell Transplantation (HSCT), 135
  John Snowden and Stephen Webber
• 22 Multiple Myeloma and Hyperviscosity Syndrome, 144
  Amin Rahemtulla and Joydeep Chakrabartty,
• 23 Palliative Care for the Patient with Haematological Malignancy in Intensive Care, 148
  Suzanne Kite

Section 6 Admission to Intensive Care

• 24 Haematological Malignancy Outside Intensive Care: Current Practice and Outcomes, 159
  Charlotte Kallmeyer
• 25 Early Care of the Unstable Patient: Preventing Admission to the Intensive Care Unit, 165
  Andrew Breen
• 26 Decisions to Intensify Treatment: Who Will Benefit from Intensive Care?, 171
  Quentin A. Hill and Peter A. Hampshire

Section 7 Point-of-Care Testing

• 27 The Relevance of Thromboelastography in Intensive Care Patients, 179
  Jon Bailey and Nicola S. Curry

Section 8 Haematology Drugs in Critical Care

• 28 Recombinant Activated Coagulation Factor VII (rFVIIa) in Critical Care, 187
  Leon Cloherty and Richard Wenstone
• 29 The Use of Haemostatic Drugs in Post-operative Bleeding, 192
  Catharina Hartman and Nigel Webster
• 30 Delivering Chemotherapy on Intensive Care, 196
  Arvind Arumainathan and Daniel Collins

Section 9 Haematology in Paediatric and Neonatal Intensive Care

• 31 Neonatal Anaemia, 207
  Michael Richards
• 32 Haemolysis, 213
  Michael Richards
• 33 Approach to Thrombocytopenia, 219
  Amrana Qureshi
• 34 Blood Component Therapy in Children and Neonates, 224
  Anne Kelly, Simon J. Stanworth and Helen V. New

Section 10 Haematological Emergencies

• 35 Haematological Emergencies, 235
  Quentin A. Hill and Amin Rahemtulla

Appendix A: Adult, Paediatric and Neonatal Haematology Reference Intervals, 243
Quentin A. Hill

Index, 249