Handbook of Immunoassay Technologies. Approaches, Performances, And Applications

1. Immunoassays: an overview
Sandeep K. Vashist and John H.T. Luong

2. Antibody immobilization and surface functionalization chemistries for immunodiagnostics
Sandeep K. Vashist and John H.T. Luong

3. Monoclonal antibody generation by phage display: history, state-of-the-art, and future
Christian Hentrich, Francisco Ylera, Christian Frisch and Achim Knappik

4. Bioanalytical requirements and regulatory guidelines for immunoassays
Sandeep Kumar Vashist and John H.T. Luong

5. Enzyme-linked immunoassays
Sandeep K. Vashist and John H.T. Luong

6. Chemiluminescent immunoassays (CLIA)
Sandeep K. Vashist and John H.T. Luong

7. Lateral flow immunoassays
Aart van Amerongen and Marjo Koets

8. Paper-based immunoassays
Zhi Liu, Jie Hu, Zhiguo Qu and Feng Xu

9. Acoustic wave-based immunoassays
Aristea Grammoustianou and Electra Gizeli

10. Interferometry-based immunoassays
P. Petrou, E. Makarona, S. Kakabakos, G. Koukouvinos, K. Misiakos and I. Raptis

11. Nanomaterial- and micromaterial-based immunoassays
Minli You, Zedong Li, Penghui Zhang, Dan Bai, Min Lin and Feng Xu

12. Microcantilever-based sensors
Sandeep K. Vashist and John H.T. Luong

13. Quartz crystal microbalance-based sensors
Sandeep K. Vashist and John H.T. Luong

14. Electrochemical immunosensors fundamentals and applications in clinical diagnostics
Kuldeep Mahato, Suveen Kumar, Ananya Srivastava, Pawan K. Maurya, Renu Singh and Pranjal Chandra

15. Lab-on-a-chip immunoassays
Sandeep K. Vashist and John H.T. Luong

16. Smartphone-based immunoassays
Sandeep K. Vashist and John H.T. Luong

17. Multiplex immunoassays
Sandeep K. Vashist and John H.T. Luong

18. Immunoassays for newborn screening
John H.T. Luong and Sandeep K. Vashist

19. Biotin interference in immunoassays and strategies to tackle it
John H.T. Luong and Sandeep K. Vashist

20. In vitro diagnostic immunoassays for SARS-CoV-2
Sandeep K. Vashist and John H.T. Luong

21. Immunoassays of human immunodeficiency virus (HIV)
John H.T. Luong

22. Immunoassays of hepatitis C virus (HCV)
John H.T. Luong and Sandeep K. Vashist

23. Immunoassays for Ebola virus disease
John H.T. Luong

24. Immunoassays of botulism neurotoxins (BoNTs) of Clostridia
John H.T. Luong

25. Immunoassays of biological warfare agents
John H.T. Luong

26. Lateral flow immunoassays with improved detection sensitivity
John H.T. Luong and Sandeep Kumar Vashist

27. Immunoassays: future prospects and possibilities
Sandeep Kumar Vashist and John H.T. Luong

Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.

Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.

• Provides comprehensive details of various types of immunoassays utilized in healthcare as well as industrial, environmental, and other biochemical settings
• Offers extensive knowledge and guided insights on multifarious aspects of immunoassays and types of immunoassays developed to date.
• Comprehensively describes immunoassay formats along with their principles of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications
• Provides technical know-how as it is written by renowned experts and key opinion leaders in the field of immunoassays with decades of experience.

Dr. Sandeep K. Vashist is the Senior Global IVD Product Director at Fapon Biotech Inc., Germany. He held senior R&D and management roles in large IVD giants, such as Bristol-Myers Squibb, Revvity (Immunodiagnostic Systems), and Trivitron Healthcare (Labsystems Diagnostics). Besides, he has been the Chief of the Research Advisory Board at Sensing Self Pte Ltd., Singapore, an Advisory Board Member at Calciscon AG, Switzerland, and a Board Member at Antrum Biotech, South Africa. Sandeep invented and pioneered many CE-certified and/or FDA-approved IVD kits, devices, and technologies. He has 12 patents, over 300 publications, 3 books, and over 9000 international citations. He is the Editor and Reviewer of several journals, funding agencies, and international organizations. Sandeep is an IVD veteran with over two decades of rich global IVD experience.

Prof John H.T. Luong was the Walton Fellow associated with the School of Chemistry of University College Cork, Ireland. He was the Professor and Division Head of Biomedical Engineering at Nanyang Technological University, Singapore. He was also a distinguished Visiting Professor at the University of Zhengzhou (China), a Visiting Professor at Nanocore, National University of Singapore, Bar-Ilan University (Ramat Gan-Israel), Institut d'Electronique, de Microélectronique et de Nanotechnologie, Université de Lille (France), and Delhi Technological University, India. He has received several awards for his excellent contribution to research, innovation, and technology transfer. He is on the Editorial Board of several Journals, the Chief Editor of MDPI Journal of Functional Biomaterials-Antimicrobials, and the Associate Editor of MDPI Macromolecule. He has 10 patents and 350 publications with over 31,000 citations with an h-index of 89. He is the expert/reviewer/advisor/consultant for many international funding agencies and enterprises.