Manual of Botulinum Toxin Therapy

1. The pretherapeutic history of botulinum neurotoxin
2. Botulinum neurotoxin: History of clinical development
3. Pharmacology of botulinum toxin therapy
4. Immunological properties of botulinum neurotoxins
5. Examination and treatment of complex cervical dystonia
6. Visualization of ultrasound guided intramuscular injections in muscles relevant for cervical dystonia
7. Ultrasound guidance for botulinum neurotoxin therapy: cervical dystonia
8. Treatment of cervical dystonia
9. Treatment of blepharospasm
10. Botulinum neurotoxin in oromandibular dystonia
11. Botulinum neurotoxin therapy of laryngeal muscle hyperactivity syndromes
12.The use of botulinum neurotoxin in otorhinolaryngology
13. Treatment of Hemifacial Spasm with Botulinum Toxin
14. Botulinum toxin in treatment of tics
15. The use of botulinum toxin in tremors
16. The role of ultrasound for botulinum neurotoxin injection in childhood spasticity
17. The use of botulinum neurotoxin in spastic infantile cerebral palsy
18. The use of botulinum neurotoxin in spasticity using ultrasound guidance
19. The use of botulinum toxin in spasticity
20. Treatment of stiff-person syndrome with botulinum toxin
21. Botulinum toxin in ophthalmology
22. Cosmetic uses of botulinum neurotoxins for the upper face
23. Botulinum toxin on the lower face
24. Botulinum Toxin in the treatment of Gummy Smile
25. Botulinum toxin for the breast
26. Treatment of depression with botulinum toxin
27. Hyperhidrosis Berthold: A treatment for ischemic digits and chronic pain
28. Botulinum toxin in the treatment for ischemic digits and chronic pain
29. Botulinum Toxin in Wound Healing
30. Use of botulinum neurotoxin in neuropathic pain
31. The Use of botulinum toxin in the management of headache disorders
32. Use of Botulinum Toxin in Musculoskeletal Pain and Arthritis
33. Treatment of plantar fasciitis/plantar fasciopathy with botulinum neurotoxins
34. Use of botulinum toxin in the treatment of low back pain
35. Use of botulinum neurotoxin in the treatment of piriformis syndrome
36. Ultrasound guided botulinum toxin injections for thoracic outlet syndrome
37. Botulinum neurotoxin in the gastrointestinal tract
38. Botulinum neurotoxin applications in urological disorders
39. Treatment of focal hand dystonia.

Providing practical, visually oriented guidance on the benefits of botulinum toxin in a wide variety of disorders, some new and unexpected, this new edition of Manual of Botulinum Toxin Therapy is fully updated in scope and detail. Chapters discuss the pathophysiology of each condition, summarizing the rationale for botulinum toxin, and describing the injection approach. Clear illustrations of the injection sites are included, using a 'clinician's eye' perspective, which allows physicians to readily identify anatomical landmarks and approach angles for injection. Dosing tables for available toxin formulations are included. The Manual covers cosmetic treatment of the upper and lower face, as well as aesthetic smile correction. Extensive guidance on how to use ultrasound and how cadaveric dissections can assist localization and targeting of injections is provided. Designed for teaching and bedside guidance, the Manual is useful to a diverse range of clinicians looking to use botulinum toxin in their practice.

• Chapters are authored by internationally renowned clinicians and investigators, ensuring content is cutting edge and valuable to professionals worldwide
• Clear and eye-catching illustrations show a 'clinician's eye view' of the injection procedure, allowing practitioners to readily identify anatomical landmarks and approach angles for injection
• Providing extensive instruction in the use of ultrasound, correlating probe positioning, on-screen image and illustrations or dissection photos of injection targets, readers will learn about the fastest growing modality for injection guidance

Daniel Truong, University of California, Riverside

Christopher Zachary, University of California, Irvine

Mayank Pathak, Truong Neuroscience Institute

Dirk Dressler, Hannover Medical School
Dirk Dressler is Full Professor of Neurology at Hannover Medical School, Hannover, Germany and Co-Director of the Neurotoxin Research Center, Tongji University Medical School, Shanghai, China. He pioneered botulinum toxin therapy in Europe.

Mark Hallett, National Institutes of Health (NIH)
Mark Hallett is an Emeritus Scientist at NIH and a former president of the International Parkinson and Movement Disorder Society. Winner of the 2017 Lifetime Achievement Award of the International Neurotoxin Association, his research focuses on the pathophysiology of movement disorders.