ABOUT THIS BOOK
The term “heavy metals” is used as a group name of toxic metals
and metalloids (semimetals) causing contaminations and ecotoxicity. In strict
chemical sense the density of heavy metals is higher than 5 g/cm3. From biological
point of view as microelements they can be divided into two major groups. a.
For their physiological function organisms and cells require essential microelements
such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b.
The other group of heavy metals is toxic to the health or environment. Of highest
concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity
of heavy metals is well known at organismal level, while less attention has
been paid to their cellular effects. This book describes the toxicity of heavy
metals on microorganisms, yeast, plant and animal cells. Other chapters of the
book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity
of several metals touch upon the aspects of environmental hazard, ecosystems
and human health. Among the cellular responses of heavy metals irregularities
in cellular mecha nisms such as gene expression, protein folding, stress signalling
pathways are among the most important ones. The final chapters deal with biosensors
and removal of heavy metals. As everybody is eating, drinking and exposed to
heavy metals on a daily basis, the spirit of the book will attract a wide audience.
Content Level » Professional/practitioner
Keywords » accumulation - apoptosis - carcinogenesis - genotoxicity - removal
Related subjects » Biomedical Sciences - Cell Biology - Environmental Toxicology - Inorganic Chemistry