Despite considerable advances in the traditional treatment modalities of surgery, radiation, and chemotherapy and their use in combination, oral cancer still presents at a relatively advanced stage, the increments in overall survival have been small, and morbidity that accompanies treatment adversely affects the quality of life. Controversy in this area is therefore inevitable. This volume brings together the work of experts from clinical and basic sciences specialties and addresses some of the controversial issues and advances in the management of oral cancer. This title features the following contributions and contributors: Potential molecular targets: From bench to bedside by Ajay Matta and Ranju Ralhan; Potentially malignant disorders of the oral cavity by D.C. Williams and W.T. McGaw; Mandible preserving alternatives by K.A. Pathak and Richard W. Nason; Surgical management of oral cancer by Richard W. Nason and K.A. Pathak; Management of the N0 neck in oral cancer by Richard W. Nason and K.A. Pathak; Current options and controversies in reconstruction of the oral cavity by Ravi Sachidananda and S.M. Taylor; Challenges in preserving salivary gland functions by Rashmi Koul and Arbind Dubey; Systemic therapies in management of head and neck cancer by A.W. Maksymiuk; and, Surveillance after treatment of oral cancer by Richard W. Nason and K.A. Pathak.