This book serves a snapshot of the current knowledge base in field. As human papillomavirus (HPV) causes a rising number of oropharyngeal cancers, understanding the biological, clinical and social implications of this infection has become increasingly important for head and neck practitioners. This book reflects the multidisciplinary nature of the scientific and clinical questions involved in this disease. Experts in epidemiology, diagnosis and treatment of HPV-related oropharyngeal cancer present in-depth reviews which will help to improve the reader’s understanding of this topic. The authors provide insight for answers of common patient and provider questions about HPV infection and related disease, and highlight remaining questions to be answered in the coming years.
Anatomical sites and subsites of head and neck cancer.- Epidemiology of oral HPV infection and HPV-associated head and neck cancer.- Frequent behavioural questions with an HPV-positive malignancy of the head and neck.- The molecular biology of HPV-related head and neck cancer.- The diagnosis of HPV-related head and neck squamous cell carcinoma: Recognition of its microscopic appearance and the use of ancillary detection assays.- Clinical management of HPV-related oropharyngeal cancer.- The role of vaccines for HPV-related head and neck cancers.- The care of the HPV-negative head and neck cancer patient: Presentation, prognosis, treatment.
CAROLE FAKHRY Department of Otolaryngology-Head and Neck Surgery The Johns Hopkins University School of Medicine Baltimore, Maryland, USA GYPSYAMBER D’SOUZA Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore, Maryland, USA