In the last few years, impressive research has been done on disorders of sex
development (DSD), largely expanding the physiopathology with relevant effects
on practice. Thus, management of individuals with DSD requires updated scientific
knowledge, integrating basic and clinical information. In addition, doctors
involved in the care of individuals with DSD need to develop specific personal
skills in communication, ethics, legal issues and the ability to work together
in dedicated multidisciplinary teams. National or even international networks
are also mandatory to create stringent structures for correctly addressing the
care of individuals with DSD and to offer them a better long-term outcome.
This special issue of Sexual Development covers several of these hot topics and highlights some aspects of research and management. A special paper from a patient support group has been enclosed to present the opinion of affected people. All the authors have been selected regarding their expertise and documented competencies.
This volume is essential reading for all scientists and clinicians involved in the field of DSD to plan additional research and to optimize the care of their patients.
Bertelloni, S. ; Hiort, O.
The European Disorder of Sex Development Registry: A Virtual Research Environment
Ahmed, S.F. ; Rodie, M. ; Jiang, J. ; Sinnott, R.O.
Ontogenesis of Testis Development and Function in Humans
Stukenborg, J.B. ; Colón, E. ; Söder, O.
New Technologies for the Identification of Novel Genetic Markers of Disorders
of Sex Development (DSD)
Bashamboo, A. ; Ledig, S. ; Wieacker, P. ; Achermann, J.C. ; McElreavey, K.
Copy Number Variants in Premature Ovarian Failure and Ovarian Dysgenesis
Ledig, S. ; Röpke, A. ; Wieacker, P.
Impact of Molecular Genetics on Congenital Adrenal Hyperplasia Management
Balsamo, A. ; Baldazzi, L. ; Menabò, S. ; Cicognani, A.
Klinefelter’s Syndrome: A Clinical and Therapeutical Update
Forti, G. ; Corona, G. ; Vignozzi, L. ; Krausz, C. ; Maggi, M.
Tumor Risk in Disorders of Sex Development
Pleskacova, J. ; Hersmus, R. ; Oosterhuis, J.W. ; Setyawati, B.A. ; Faradz, S.M. ; Cools, M. ; Wolffenbuttel, K.P. ; Lebl, J. ; Drop, S.L. ; Looijenga, L.H.
Bone Health in Disorders of Sex Differentiation
Bertelloni, S. ; Baroncelli, G.I. ; Mora, S.
A Study of Gender Outcome of Egyptian Patients with 46,XY Disorder of Sex
Ismail, S.I. ; Mazen, I.A.
Management of Vaginal Hypoplasia in Disorders of Sexual Development: Surgical
and Non-Surgical Options
Deans, R. ; Berra, M. ; Creighton, S.M.
Ethical Guidelines for the Clinical Management of Intersex
Disclosing Disorders of Sex Development and Opening the Doors
Importance of Support Groups for Intersex (Disorders of Sex Development) Patients,
Families and the Medical Profession
Cull, M.L. ; Simmonds, M.
Author Index Vol. 4, No. 4–5, 2010