Neuroendocrine Tumours. Diagnosis and Management

Description

Since neuroendocrine tumors (NETs) are relatively rare, they have in the past attracted limited research interest and only a small number of oncologists have regarded them as a special concern. Fortunately, this situation is changing. There have been significant recent developments in our understanding of NETs and new treatment options have become available, stimulating a focus on further research and the scope for additional therapeutic advances. Neuroendocrine Tumors is therefore a timely textbook that covers all aspects of the subject, from epidemiology, pathological classification and evaluation, and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas, and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists, and pathologists and also trainees.?

Table of Contents

Introduction.- Historical backgroud.- Epidemiology.- Pathological Classification.- Carcinoid syndome.- Moleculer biology.- Insulinoma.- Gastrinoma.- Vipoma.- Glucagoma.- Pathological Evaluation.- Radiological Imaging.- Nuclear Imaging.- Genetic syndromes associated with NET.- Surgical Approach.- Locoregional treatment (RFA).- Embolization (Chemo/radio).- PRRT.- Management of hormonal symptoms.- Chemotherapy.- Somatostatin analogues.- Targeted therapies.- Guidelines.- Societies and guidelines.- Biomarkers.- Medullary thyroid cancer.- Adrenocortical cancer.- Paraganglioma, feokromostoma.- Nonfonksiyone pNET.- Somatostatinoma.- Poorly differentiated NET.- Management of MEN.- Ppoma.