This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers.
All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.
- Brings together the world's leading experts in the field of Leptospira
- Provides understanding of host-pathogen interactions in leptospirosis at the cellular and molecular level
- Covers all aspects of Leptospira and leptospirosis, from taxonomy, practical aspects of human and animal infections and management, through to the most recent developments in genomics and in understanding immunity and pathogenesis ?
History of Leptospirosis and Leptospira
Systematics of Leptospiraceae
Paul N. Levett
Leptospiral Structure, Physiology and Metabolism
Caroline E. Cameron
Genomics, Proteomics and Genetics of Leptospira
Leptospirosis in Humans
David A. Haake and Paul N. Levett
William A. Ellis
The Molecular Basis of Leptospiral Pathogenesis
Gerald L. Murray
The Leptospiral Outer Membrane
David A. Haake and Wolfram R. Zückert
Host response to Leptospira Infection
Richard L. Zuerner
Vaccines Against Leptospirosis
The Role of Leptospirosis Reference Laboratories
Rudy A Hartskeerl and Lee D Smythe