


Interleukin-10 in Health and Disease (Current Topics in Microbiology and Immunology, Vol. 380)
Fillatreau, S. — O'Garra, A.
ISBN-13: 9783662434918
SPRINGER
Agosto / 2014
1ª Edición
Inglés
Tapa dura
238 pags
516 gr
16 x 24 x 2 cm
Recíbelo en un plazo De 2 a 3 semanas
Description
· Resents an in-depth and global analysis of how IL-10 contributes to
immunity
· Offers a set of reviews dedicated to the biology of IL-10
· Provides a comprehensive overview on one of the most important anti-inflammatory
cytokines
This volume provides a set of reviews dedicated to the biology of Interleukin
(IL)-10. It includes chapters on its importance for maintaining immune homeostasis
in humans, its role in intestinal immunity and its functions during viral and
bacterial infections. In addition, it presents reviews on the mechanisms linking
innate microbial recognition to the production of IL-10 and on how IL-10 recognition
by its receptor functions. The roles of T and B cells as relevant sources of
IL-10 are also discussed, with an emphasis on the clinical opportunities offered
by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally,
the functions of other cytokines of the IL-10 family are presented. Collectively,
these articles provide a comprehensive overview of our current knowledge on
one of the most important anti-inflammatory cytokines known to date.
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