Broad and up-to-date overview of immunology of the female genital tract Discusses results from the most important recent studies Encompasses the immunology of viral and bacterial infections, the immunology of pregnancy, and immunological infertility
The mucosal immune system in the female reproductive tract has evolved to meet the unique requirements deriving from the need to deal with sexually transmitted bacterial and viral pathogens, allogeneic spermatozoa, and the immunologically distinct fetus. Despite years of immunologic investigation, the mechanisms that regulate this mucosal immune system have received relatively little attention. This is due to the complexities of the immune and endocrine system and also the difficulties of conducting experiments in this field. This book systematically reviews and discusses recent studies and articles on the immunology of female genital tract tissue. The scope is broad, encompassing innate immune responses, adaptive (humoral and cell-mediated) immunity, the immunology of menstruation, the immunology of viral and bacterial infections, the immunology of normal and abnormal pregnancy, and immunological infertility. Throughout, tables and illustrations are judiciously used to facilitate understanding. Immunology of the Female Genital Tract will serve as an invaluable source of up-to-date information for all with an interest in this subject.
Content Level » Professional/practitioner
Keywords » Female genital tract tissue - Female reproductive tract - Mucosal immune system - Sexually transmitted bacterial and viral pathogens
Related subjects » Dermatology - Gynecology - Immunology - Public Health - Urology
TABLE OF CONTENTS
Fundamentals of immunology: Concepts of innate and specific immunity.- Mucosal immunology.- General immunology of the genital tract: Distinct features of the genital mucosal tissue.- Functions and regulation of innate immune responses in the human reproductive tract.- Functions and regulation of adaptive humoral and cell-mediated immunity in the female genital tract.- Immunization studies.- Immunology of menstruation – menstruation as an inflammatory process.- Immunology of genital tract infections: Viral infections of the genital tract.- Bacterial infections of the genital tract.- Candidiasis.- Trichomoniasis.- Immunology in reproductive medicine: Immunology of pregnancy.- Immunologic infertility.- Immunocontraceptive approaches.
AUTHORS & EDITORS
Professor Ernst Rainer Weissenbacher is Director of the Clinic and Polyclinic for Gynecology and Obstetrics at Großhadern Clinic, Ludwig Maximilians University of Munich. He is also President of the European Society for Infectious Diseases in Obstetrics and Gynecology. Professor Weissenbacher is recognized as a leading authority in the field and has written several books as well as many journal articles. He has a particular interest in the care of high-risk pregnancies and the treatment of infections of the female genital tract, and has also been a strong proponent of use of the Gardasil vaccine to combat cervical cancer.