Advanced Imaging in Biology and Medicine (Hardcover)

About this book

Since the invention of X-Ray technology by Konrad Roentgen in 1895, non-invasive imaging technologies are part of the medical and biological tool kit. Today, quite a number of non-invasive imaging technologies exist, from 4-dimensional Ultrasound to Computer Tomography. Almost every individual is subjected to one or more of these technologies during their lifetime. Destructive imaging approaches such as light- and electron microscopy have benefitted from the development of computing algorithms and digital imaging, making them more and more valuable for the study of biological and medical phenomena.

Not only is the number of imaging technologies increasing rapidly, at the same time the strategies and algorithms for image analysis are becoming more and more sophisticated. This book attempts for the first time to provide an overview of the major approaches to biological and medical imaging, the strategies for image analysis and the creation of models, which are based on the results of image analysis. This sets the book aside from the usual monographs, which introduce the reader only to a single technology.

Given the broad range of topics covered, this book provides an overview of the field, which is useful for a wide audience, from physicians and biologists to readers who would like to know more about the technology, which is used to derive diagnoses of diseases today.

Written for: Researchers and clinicians in the field of imaging technologies

Keywords:

• functional MRI
• image-based modeling
• imaging applications
• imaging software
• micro CT

Contents

Part I Imaging Technologies

1 Micro-Computed Tomography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Steven K. Boyd

2 Advanced Experimental Magnetic Resonance Imaging . . . . . . . . . . . . 27
Ursula I. Tuor

3 Freehand 3D Ultrasound Calibration: A Review . . . . . . . . . . . . . . . . . 47
Po-Wei Hsu, RichardW. Prager, Andrew H. Gee, and Graham M. Treece

4 Laser Scanning: 3D Analysis of Biological Surfaces . . . . . . . . . . . . . . . 85
Matthew W. Tocheri

5 Optical Coherence Tomography: Technique and Applications . . . . . . 103
J.B. Thomsen, B. Sander, M. Mogensen, L. Thrane, T.M. Jørgensen, G.B.E. Jemec, and P.E. Andersen

6 Mass Spectrometry-Based Tissue Imaging . . . . . . . . . . . . . . . . . . . . . . . 131
Carol E. Parker, Derek Smith, Detlev Suckau, and Christoph H. Borchers

7 Imaging and Evaluating Live Tissues at the Microscopic Level . . . . . 147
John Robert Matyas

8 Ultrastructure Imaging: Imaging and Probing the Structure
and Molecular Make-Up of Cells and Tissues . . . . . . . . . . . . . . . . . . . . 171
M. Amrein

9 Optical Projection Tomography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
James Sharpe

10 Medical Imaging Modalities – An Introduction. . . . . . . . . . . . . . . . . . . 225
J¨org Peter

Part II Software

11 Volume Visualization Using Virtual Reality . . . . . . . . . . . . . . . . . . . . . . 257
Anton H.J. Koning

12 Surface Modeling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271
Andrei L. Turinsky

13 CAVEman, An Object-OrientedModel of the Human Body . . . . . . . . 289
ChristophW. Sensen and Jung Soh

14 Image-Based Finite Element Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . 301
Steven K. Boyd

15 GeometricMorphometrics and the Study of Development . . . . . . . . . 319
Benedikt Hallgr´imsson, Julia C. Boughner, Andrei Turinsky,
Trish E. Parsons, Cairine Logan, and ChristophW. Sensen

Part III Applications

16 Imaging in Audiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339
Jos J. Eggermont

17 Applications of Molecular Imaging with MR. . . . . . . . . . . . . . . . . . . . . 363
Linda B. Andersen and Richard Frayne

18 Genomic Data Visualization: The Bluejay System . . . . . . . . . . . . . . . . 395
Jung Soh, Paul M.K. Gordon, and ChristophW. Sensen

19 Anatomical Imaging and Post-Genomic Biology . . . . . . . . . . . . . . . . . . 411
Benedikt Hallgr´imsson and Nicholas Jones

20 Functional Measures of Therapy Based on Radiological Imaging . . . 427
David Dean, Nathan Cross, Davood Varghai, Nancy L. Oleinick, and Chris A. Flask

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439