Series editor's preface
01 Long-lived cells and long-lived proteins in the human body
02 Imaging Mass Spectrometry of Long-Lived Proteins
03 Eye lens crystallins: remarkable long-lived proteins
04 Spontaneous breakdown of long-lived proteins in aging and their implications in disease
05 Modifications of Long-lived Proteins that affect Protein Solubility
06 Degradation of Long-lived proteins as a cause of Autoimmune diseases
07 How Isomerization and Epimerization in Long-lived Proteins Affects Lysosomal Degradation and Proteostasis
08 The Maillard Reaction. Protein Modification by Ascorbic Acid
This comprehensive overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins and their role in age-related diseases and in determining human lifespan.
Roger Truscott is a Research Professor at the Illawarra Health and Medical Research Institute, University of Wollongong. Having obtained his PhD at Melbourne University, he has spent most of his academic career working for the University of Sydney and the University of Wollongong. He has authored over 200 scientific publications. His main field of research is human aging with particular reference to age-related diseases, such as cataract. He has received numerous awards including a senior NHMRC fellowship and the National Foundation for Eye Research (USA) Cataract Research Award.