Provides new insights into the mechanisms causing cell death
Presents recent studies on various types of non-apoptotic forms of cell death including regulated necrosis, pyroptosis, entosis, and ferroptosis
Shows that apoptotic cells release various factors that are involved in inflammation, proliferation, immune tolerance, and tissue repair in a context dependent manner
This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skindiseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells. Offering insights intocell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.
Shigekazu Nagata is a professor of Graduate School of Medicine, Kyoto University, Japan. Hiroyasu Nakano is a professor of Graduate School of Medicine, Toho University, Japan.