Overweight and obesity have become a global pandemic that has major health and economic consequences. The global transition in food consumption and in physical activity habits probably plays an important role as discussed by various authors in numerous countries. Concerning nutritional considerations related to obesity, the health impact of fluid intake is commonly neglected, and fluid intake advices are missing in most of the food pyramids offered to the public. Delineation of global health benefits of a healthier hydration merits more attention. It is of major importance to establish healthier hydration behaviour that might play a role in curbing the curve of obesity progression. The Proceedings of the 5th Annual Scientific Conference of the Hydration for Health Initiative which was organised within the long-term programme of Hydration for Health Meetings and sponsored by Danone Waters and Danone Research focuses on the latest findings and gives a concise overview.