Adverse Drug Reactions in the Orofacial Region: How Does it Work?.- Drug-Induced Gingival Overgrowth.- Drug-Induced Oral Mucosa Pigmentation.- Oral Manifestations of Drug Allergy.- Drug-Induced Oral Ulcerations.- Drug-Induced Oral Lichenoid Reactions / White Lesions.- Drug-Induced Osseous Complications.- Drug-Induced Oral Bleeding.- Drug-Induced Taste Disturbances.- Drug-Induced Salivary Gland Disturbances : Xerostomia, Pain, Swelling, Hypersalivation, Discoloration of Saliva.- Drug-Induced Oral Infections.- Drug-Induced Peri-Oral and Facial Complications.
This book provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance. It will be of value for all dental and medical practitioners who encounter these complications in their clinical practice.
Sarah Cousty, DDS, PhD, works at the Dental Faculty and the Centre Hospitalier Universitaire de Toulouse (University Hospital), France, where she is a Professor and Senior Lecturer and Hospital Practitioner in Oral Surgery. In 2002, Dr. Cousty gained a Masters Degree in Biological and Medical Sciences and a Degree in Epidemiology (applied to dental research) at Paul Sabatier University in Toulouse. She went on to obtain her DDS at the same university in 2004 (First Class Honors, silver medalist) and completed a PhD in Electrical Engineering, Electrotechnical studies and Telecommunications in 2007. She took up her present position in 2008.
Sara Laurencin-Dalicieux, DDS, PhD, works at the Dental Faculty and the Centre Hospitalier Universitaire de Toulouse (University Hospital), France, where she is a Senior Lecturer and Hospital Practitioner in Periodontology. In 2003, Dr. Laurencin-Dalicieux completed a Masters Degree in Biological and Medical Sciences and her DDS (First Class Honors, bronze medalist) at Paul Sabatier University in Toulouse. She gained a PhD in Biology, Health and Biotechnologies and a Degree in Periodontology from the same university in 2010 and 2011, respectively. She took up her current position in 2013.
Both authors are in currently charge of the multidisciplinary oral mucosa consultation in Toulouse's University Hospital which interracts and finds itself at the crossroad of other medical specialties such as Dermatology, Maxillo-facial Surgery, ENT and Internal Medicine.