This book provides readers with a discussion of the current state of the art and an overview of this infection, which is one of the most common causes of sexually transmitted diseases worldwide, both in men and women. This handbook provides the scientific background needed to understand the natural history and pathogenesis of this important infection. The text is composed of chapters that explore the epidemiology, clinical features, diagnosis, treatment and prevention of HPV infections. Also, the book provides a special section focused on the new vaccines recently introduced, their efficacy, their application worldwide and, above all, the new epidemiological perspectives for this infection in the future after the application of the vaccines.
• Covers all of the important issues related to HPV
• Addresses the topics in terms of both male and female infection
• Provides the current knowledge about epidemiology, basic virology, pathogenesis and diagnosis methods
• Explores the relationship between HPV infection and cancer
• Adds new information about the treatment methods for this infection
• Introduces a special chapter about prevention strategies such as vaccine introduction
- Introduction and epidemiological data
- Basic virology: structure and nomenclature
- Natural history and transmission. Anatomic distribution
- HPV infection and association with cancer
- Diagnosis of HPV infection - methods of specimen collection; conventional and monolayer cytology; histopathology; HPV DNA detection; DNA Hybridization; type-specific and general primer PCR; capture of RNA-DNA Hybrids: liquid hybridization; HPV mRNA detection
- Clinical Utility of HPV testing
- Prevention: HPV vaccines - HPV vaccine types; composition; dose and administration; immunogenicity and efficacy; safety and adverse events; impact of vaccination and cost effectiveness; recommendations for use of HPV vaccine; recommendations for routine use; vaccination during pregnancy; precautions and contraindications; HPV vaccine acceptance; new epidemiological data after vaccine implementation; and areas for research in HPV vaccines
Practitioners: microbiologists, pathologists, infectologists, gynaecologists, primary health care physicians (family doctors), primary health care nurses and epidemiologists. Researchers, students, pre-doc and post-doc and laboratory workers.
Cobo, Fernando Dr
Dr Fernando Cobo is a Doctor specialist in Microbiology and works at the Microbiology Section at the Hospital de Poniente, Almeria, Spain. He received his M.D. from the University of Valencia (Spain) and his PhD from the University of Granada (Spain). Over the last five years he has worked as a doctor in medicine, and a researcher and microbiologist at the Infectious Pathology Unit of the University Hospital Virgen de las Nieves (Granada, Spain), and he also worked as microbiology advisor at the Stem Cell Bank of Andalucia (Granada, Spain). During this period, he implemented in this laboratory some methods of HPV detection (InnoLipa, Microarrays, Real Time PCR) in several types of samples. Dr. Fernando Cobo is a member of several professional societies such as the Spanish Society of Infectious Diseases and Clinical Microbiology.
He has published over 50 peer reviewed journal articles, 10 books, 90 book chapters and 120 national and international meeting and congress presentations. He has collaborated as referee in several journals (i.e. Clinical Transplantation, Biomaterials, Journal of Immunological Methods, etc), and he is an Editorial Board Member of some journals (The Open Virology Journal, The Open Biotechnology Journal, Experimental Medicine, Microbiology Insights and World Journal of Stem Cell Research).