Handbook of Cushing’s Disease

Description

It is 100 years since Harvey Cushing described the disease that now bears his name. We are now at a new and exciting phase of understanding and treating Cushing’s disease. This handbook aims to offer easily accessible insights into the clinical, biochemical, and radiological diagnosis of Cushing’s disease, as well as in the current surgical, radiotherapeutic and medical treatments available to these patients.

Contents

• Clinical diagnosis: signs, symptoms, epidemiology
  Günter Karl Stalla, Christina Dimopoulou, Germany
• Diagnosis, sampling and imaging
  Lynnette K Nieman, USA
• Mortality, systemic and psychiatric complications
  Annamaria Colao, Monica De Leo, Rosario Pivonello, Gaetano Lombardi, Italy
• Quality of life and long-term follow-up
  Susan M Webb, Alicia Santos, Eugenia Resmini, Elena Valassi, M’Antonia Martínez, Olga Roig, Iris Crespo, Xavier Badia, Spain
• Surgical management and radiotherapy
  Michael Buchfelder, Sven Schlaffer, Germany
• Definition of clinical remission vs. biochemical remission
  John Newell-Price, UK
• Medical therapy with ketoconazole and mifepristone
  Frederic Castinetti, Thierry Brue, France
• Membrane receptors on corticotrophinomas: therapeutic targets
  Leo J Hofland, The Netherlands
• Medical therapy with dopamine receptor analogues
  Rosario Pivonello, Monica De Leo, Alessia Cozzolino, Pasquale Vitale, Maria Cristina De Martino, Annamaria Colao, Italy
• Medical therapy with pasireotide
  Stephan Petersenn, Germany
• Medical combination therapy for Cushing’s disease
  Richard A Feelders, The Netherlands
• Practical aspects of the management of patients with Cushing’s disease
  Josephine I Tuthill, John AH Wass, UK
• Future prospects
  Steven WJ Lamberts, The Netherlands