Understanding the many complex cellular and molecular mechanisms underlying human vascular diseases is essential in improving the management of patients with this clinically important and wide-ranging group of diseases. This is particularly important when considering the extent of this issue across the world.
Written by a team of world-renowned authorities, Advances in Vascular Medicine highlights some of the relationships between basic science and clinical medicine, and reviews both research and clinical practice methods and outcomes in vascular biology and pathobiology. It is an authoritative reference for these important topics of vascular biology and includes chapters that explain the clinical issues to the basic scientist as well as providing clinicians with a scientific grounding in vascular diseases. Although there is still much work to be done to advance understanding of vascular disease, the information and insights contained in this book are a vital contribution to the literature, giving scientists and clinicians the opportunity to learn more about this exciting field of biomedicine.
Written for: Clinicians and basic scientists in all fields of medicine
Section 1: Mediators of endothelial cell function and vascular disease.The biology of nitric oxide.- Red wine and vascular health.- Endothelin in vascular disease.- Section 2: Pulmonary arterial hypertension. Clinical developments and visions for managing pulmonary arterial hypertension.- Pulmonary arterial hypertension in connective tissue diseases.- Endothelial progenitor cells and vascular repair in pulmonary arterial hypertension. Section 3: Surgical intervention of vascular complications of disease.Cardiovascular surgery in the 21st century.- Thromboendarterectomy in chronic thromboembolic disease pulmonary hypertension.- Coronary artery surgery – the "no-touch" approach.- Role of perivascular adipose tissue on vascular function. Section 4: Genetics and gene therapies. Genes and genetics of pulmonary arterial hypertension.-Genetics of coronary disease.- Gene therapy for cardiovascular disease.