Vasopressin is a hormone which has an increasingly important profile. Not only does it play a physiologically significant role in renal water regulation but it also has other renal actions and plays a role in overall cardiovascular control. Even more interesting is the recent growing interest in its potential effects on the brain, notably its influence on specific behaviours.
This monograph about the polypeptide vasopressin covers all aspects relating
to the production, control of release, and actions of this molecule within the
body, including its roles as a hormone and as a central neurotransmitter. A
consideration of the evolution of the molecule across the species and a brief
historical perspective are also included. Clinical conditions associated with
hypo- and hyper-production states are considered together with aspects of treatment,
in addition to other clinical correlates.
Introduction to Vasopressin
Comparative and Evolutionary Aspects of Vasopressin
The Neurohypophysial System: Synthesis and Metabolism of Vasopressin
Vasopressin Receptors, the Signalling Cascade and Mechanisms of Action
Pharmacology of the Vasopressin Receptors
Vasopressin and Its Renal Effects
Vasopressin and the Cardiovascular System
Vasopressin and Its Interactions with Other Hormones and Control Systems
Understanding the Role of Vasopressin in the Hypothalamo-Pituitary Adrenocortical Axis
Vasopressin: The Central Systems
Vasopressin Secretion: Mechanisms of Control of Secretion from the Posterior Pituitary Gland
Clinical Aspects of Vasopressin
Readership: Academics, researchers, and postgraduates in the field of endocrinology.