As the incidence of asthma in the adult population continues to increase, and
the age of onset in children to decrease, this condition remains a primary concern
not only for specialists in respiratory medicine, but also for physicians in
many other fields, when dealing with the asthmatic patient. The range of therapeutic
agents now available, and the diversity of targets on which they act, presents
the doctor with a variety of options for managing the condition. In this volume
leading international authorities explain the mechanisms of action of the drugs
currently in use, and their clinical applications, singly and in combination.
Asthma: Current Treatments provides physicians with a comprehensive resource
that will help them evaluate for themselves the right approach for each of their
patients. It will be of also be of interest to other health professionals involved
in the care of patients being treated for this condition.
FIRST LINE ANTI-INFLAMMATORY AND BRONCHODILATOR DRUGS
1. Novel mechanistic aspects of GCS in relation to asthma therapy. I Adcock
2. Benefit-risk of long-acting ß-adrenergic and ultra long-acting ß-adrenergic agonists.
M Cazzola, J Lötvall, MG Matera
3. Non-bronchodilator activities of beta2-agonists: enhanced efficacy in the management of asthma?
4. The pros and cons of combination therapy. J Lötvall
NOVEL APPROACHES TO BRONCHODILATION
5. Controversies on antileukotrienes. S Salvi
6. Role of PDE4 in asthma. G Currie
7. Anti-cholinergics in asthma? C Virchow
8. The new role of anti-IgE therapy in the treatment of asthma. C Oliveri, R Polosa,
9. Life, death and resurrection of allergen immunotherapy in asthma. R Polosa
10. Role of CpG DNA in asthma. D Gor, J Kline
11. Putative role of antimicrobial activity in asthma treatment. P Tarsia, S Aliberti,
M Pappalettera, M Zanardelli, F Blasi
SUBPHENOTYPE CENTERED THERAPY
12. What is new in the management of acute asthma? GJ Rodrigo
13. Rethinking individualized treatment of asthma. FE Hargreave
14. Determinants of therapeutic response in asthma: cigarette smoking. M Spears,
R Chaudhuri, NC Thomson
· Presents a comprehensive review of current treatment options · Latest guidelines on clinical management reviewed from an international perspective · Provides background on pharmacology and mechanisms of drug action · Provides a key resource for individual patient care
Specialists in respiratory medicine, allergy and immunology ? General physicians ? Clinical pharmacologists ? Doctors in training
R Polosa, Presidio Ospedaliero Ascoli-Tomaselli, Catania, Italy; ST Holgate, Southampton General Hospital, Southampton, UK.