Transcranial Magnetic Stimulation (TMS) is one of the principal research methods used in systems, cognitive and clinical neuroscience. Originally envisioned as a way to measure the responsiveness and conduction speed of neurons and synapses in the brain and spinal cord, TMS has also become an important tool for changing the activity of brain neurons and the functions they underpinned; and as an important adjunct to brain imaging and mapping techniques. Recently, TMS has become a therapeutic technique for neurological as well and psychiatric disorders. This book aims to bring together the basic science, fundamental principles and essential procedures of Transcranial Magnetic Stimulation (TMS), as well as its current and potential clinical applications. The first and second parts of the book present overviews of the principles of TMS, methodological issues in TMS research, the effect of TMS in the brain and its mechanism of action. These chapters also present novel data about cognitive mechanisms in the healthy brain as investigated by using TMS. The next two sections summarise state-of the-art therapeutic uses of TMS in neurological diseases and Psychiatric disorders. TMS use is evaluated in chronic as well as acute conditions. Moreover, novel potential therapeutic interventions are suggested for some diseases in which further research using TMS is warranted. Finally, the use of TMS for children and adolescents with developmental disorders is discussed, and safety protocols for TMS treatment in the developing brain are proposed. This book should be of interest for researchers in neuroscience, neurologists, psychiatrists and psychologists.
Table of Contents
Preface; Introduction; Transcranial Magnetic Stimulation: A Brief Conspectus & Area of Therapeutic Application; TMS Studies of the Cerebello-Cortical Pathway; Numerical Simulation of Deep Brain Transcranial Magnetic Stimulation; Beyond Inhibition: Exploiting the Potential of State-Dependency in Cognitive & Therapeutic TMS Studies; The Use of TMS in Measuring Motor Cortical Activity in Response to Dual Tasking; Transcranial Magnetic Stimulation Studies in Schizophrenia: Application in Clinical Studies; Demonstrating the Pathophysiology of Auditory Hallucinations with Transcranial Magnetic Stimulation; Transcranial Magnetic Stimulation & Obsessive-Compulsive Disorder: Current & Future Approaches; rTMS in the Treatment of Major Depression: Challenges & New Directions; rTMS for Chronic Tinnitus; Combined Application of Therapeutic Repetitive Transcranial Magnetic Stimulation & Intensive Rehabilitative Program: A Novel Approach for Upper Limb Hemiparesis after Stroke; Applications of Transcranial Magnetic Stimulation in the Developing Brain; Transcranial Magnetic Stimulation in Autism Spectrum Disorders; Index.