Animal Models for Retinal Diseases (Series: Neuromethods, Vol. 46)

ABOUT THIS BOOK

· Provides an easily accessible authoritative reference for animal models of the most common and important retinal diseases
· Covers macular degeneration, retinal degeneration, diabetic retinopathy, glaucoma, retinopathy of prematurity, retinal ischemia, and retinal inflammation
· Details methods for the functional, morphological, and molecular assessment of the retina in animal models of retinal diseases
· Includes authoritative introductions into retinal morphology, retinal genetics, and visual function

Affecting over a hundred million individuals worldwide, retinal diseases are among the leading causes of irreversible visual impairment and blindness, and appropriate study models, especially animal models, are essential to furthering our understanding of the etiology, pathology, and progression of these endemic diseases. In Animal Models for Retinal Diseases, recognized experts in the field highlight valuable techniques as well as animal models for the prominent retinal diseases in order to aid in the evaluation, development, and improvement of therapeutic strategies. Beginning with an overview of the morphology of the retina, visual behavior, and genetics and genomics approaches for retinal research, the book continues by covering animal models for the research of specific human retinal diseases, e.g., retinal degeneration, age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, glaucoma, retinal ischemia, and retinal inflammation. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used approaches in the field.

Vital and easy to use, Animal Models for Retinal Diseases serves to support the important future research of ocular investigators, ophthalmologists, and neuroscientists currently delving into this fascinating field of study.

Written for » Professional/practitioner
Keywords » Diabetic retinopathy - Glaucoma - Inflammation of the retina - Macular degeneration - Ophthalmology - Retinal ischemia
Related subjects » Neuroscience

TABLE OF CONTENTS

1. Essentials of Retinal Morphology
Robert F. Mullins and Jessica M. Skeie

2. Visual Behavior
Robert M. Douglas, Trevor J. McGill, and Glen T. Prusky

3. Genetic and Genomic Approaches for Understanding Retinal Diseases
Gareth R. Howell and Simon W.M. John

4. Animal Models for Retinal Degeneration
Marijana Samardzija, Stephan C.F. Neuhauss, Sandrine Joly, Malaika Kurz-Levin, and Christian Grimm

5. Animal Models for Age-Related Macular Degeneration
Joe G. Hollyfield and Lisa Kuttner-Kondo

6. Animal Models of Retinopathy of Prematurity
Susan E. Yanni and John S. Penn

7. Animal Models of Diabetic Retinopathy
Adrian M. Timmers, Casey M. Miller, and Li Zhu

8. Non-Primate Models for Glaucoma Retinopathy and Optic Neuropathy
Iok-Hou Pang and Abbot F. Clark

9. Primate Glaucoma Models
Ronald S. Harwerth

10. Animal Models of Retinal Ischemia
Jacky Man Kwong Kwong and Joseph Caprioli

11. Retinal Inflammation: Uveitis/Uveoretinitis
Reiko Horai and Rachel R. Caspi