A Guide to Paediatric Red Blood Cell Disorders

Preface

Part 1: Basic Concepts and an Approach to Red Blood Cell Disorders

• Chapter 1. Red Blood Cells and Haemoglobin
• Chapter 2. Evaluation of Childhood Anaemia

Part 2: Microcytic Anaemias

• Chapter 3. Iron Deficiency Anaemia
• Chapter 4. Thalassaemia
• Chapter 5. Sickle Cell Disease
• Chapter 6. Other Microcytic Anaemias

Part 3: Normocytic Anaemias

• Chapter 7. Hereditary Spherocytosis and Other Membranopathies
• Chapter 8. Glucose 6-Phosphate Dehydrogenase Deficiency and Other Enzymopathies
• Chapter 9. Autoimmune Haemolytic Anaemias
• Chapter 10. Microangiopathic Haemolytic Anaemias
• Chapter 11. Neonatal Anaemias
• Chapter 12. Other Normocytic Anaemias 

Part 4: Macrocytic Anaemias

• Chapter 13. Megaloblastic Anaemia
• Chapter 14. Red Blood Cell Aplasia
• Chapter 15. Other Macrocytic Anaemias 

Part 5: Polycythaemia

• Chapter 16. Neonatal Polycythaemia
• Chapter 17. Childhood Polycythaemia

Index

A Guide to Paediatric Red Blood Cell Disorders is a comprehensive text on common red blood cell disorders encountered in children. It is a useful guide to postgraduate doctors training in paediatrics and haematology, medical undergraduates, primary care physicians and practising clinicians. The book is divided into five sections. The first section provides a detailed understanding of the basic concepts and approach to red blood cell disorders in children. This section includes information on the structure and function of red blood cells and haemoglobin, epidemiology and aetiology of anaemia and clinical and laboratory evaluation of childhood anaemia. The next three sections will provide information on paediatric conditions that result in microcytic, normocytic and macrocytic anaemia, respectively. The final section will be on conditions leading to polycythaemia in neonates and children. Throughout the book, the emphasis is given to common conditions that are frequently encountered in clinical practice. However, rare but clinically important conditions have also been included. Each chapter is divided into subheadings to describe the epidemiology, aetiology, genetic basis, molecular pathology, pathophysiology, classification, clinical features, investigations, diagnosis, treatment, follow-up and prognosis of each disorder. At the end of each chapter, a section on recent advances provides information on promising novel developments and experimental approaches for treating these diseases. This book will help medical undergraduates to grasp concepts and understand the entire spectrum of red blood cell disorders in children. For practising clinicians, this will be a useful guide on how to approach a child with anaemia, which is one of the most common presentations to general practice, field clinics and hospitals. For postgraduate doctors training in paediatrics and haematology, the book will provide comprehensive information on how to manage common as well as complex red blood cell disorders in children. This book is concise, reader-friendly and written in simple English, which can be understood by non-native speakers. It will aid readers across the globe to grasp the concepts of paediatric red blood cell disorders easily and be knowledgeable and up to date in managing these patients.