Chapter 1. Insights into the Molecular Drivers of Prostate Cancer
(Sonal M. Manohar, Assistant Professor, Biological Sciences, Sunandan Divatia School of Science, NMIMS University, Vile Parle, Mumbai, India)
Chapter 2. Lung Cancer Early Diagnosis: The Sooner, the Better
(Giulia Sedda, PhD, Roberto Gasparri, PhD, and Lorenzo Spaggiari, PhD, Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy, and others)
Chapter 3. Smoking Exposure Accelerated the Normal Lung to Become Cancers
(Jia-Ping Wu, Research Center for Healthcare Industry Innovation, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan)
Chapter 4. Lymph Nodes Mediastinal Staging in Lung Cancer: A Critical Appraisal
(Federica Danuzzo, Luca Bertolaccini, Juliana Guarize, Stefano Donghi, Niccolò Filippi, Lara Girelli and Lorenzo Spaggiari, Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy, and others)
Chapter 5. Calcium Signalling in Cancer: A Focus on Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) in Colorectal Cancer
(S. Y. N. Jamaludin, PhD, and A. H. Jahidin, PhD, Faculty of Medicine, Universiti Sultan Zainal Abidin, Medical Campus, Kuala Terengganu, Terengganu, Malaysia, and others)
Chapter 6. Breast Cancer: Signs, Symptoms and Management
(Serap Korkmaz, Department of Education, Gulhane Education and Research Hospital, University of Health Sciences, Ankara, Turkey)
Chapter 7. Increased CO2 Percentage as a Tool for Reducing Cell Culture Medium pH
(Brian S. Backer and Clifford E. Berkman, Department of Chemistry, Washington State University, Pullman, WA, US)
In Horizons in Cancer Research. Volume 76, the molecular drivers associated with prostate cancers at different stages which can be exploited as drug targets are discussed. This information will be useful for designing rational targeted therapeutic strategies for treatment of this disease.
Following this, the authors discuss lung cancer early diagnosis with traditional and alternative approaches.
In lung cancer, smoking exposure has been identified as the main causative agent in smokers.
A critical appraisal of the different updated techniques in the mediastinal staging of lymph nodes in lung cancer is provided.
The authors also provide an overview of colorectal cancer and Ca2+ signalling in cells, focusing their discussion on a specific component of the Ca2+ signalling machinery, the transient receptor potential cation channel subfamily V member 4 channel.
Breast cancer, a serious public health problem, is assessed, maintaining that women need accurate and effective information in order to attain early diagnosis.
Lastly, a simple technique to decreases cell-culture pH while maintaining sterile technique is described.