Core Concepts in Acute Kidney Injury

Part I Epidemiology and Diagnosis

Chapter 1 Epidemiology, Incidence, Risk Factors, and Outcomes of Acute Kidney Injury
Chapter 2 Definition and Classification of Acute Kidney Injury
Chapter 3 Diagnostic Approach: Differential Diagnosis, Physical Exam, Lab Tests, Imaging and Novel Biomarkers

Part II Pathophysiology

Chapter 4 Overview of Pathophysiology of Acute Kidney Injury: Human Evidence, Mechanisms, Pathological Correlations and Biomarkers, and Animal Models
Chapter 5 Tubular Physiology in Acute Kidney Injury: Cell Signaling, Injury, and Inflammation

Part III Clinical Syndromes

Chapter 6 Contrast-Associated Acute Kidney Injury
Chapter 7 Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, Outcomes
Chapter 8 Acute Kidney Injury and Cancer: Incidence, Pathophysiology, Prevention/Treatment, Outcomes
Chapter 9 Drug-Induced Acute Kidney Injury
Chapter 10 Sepsis and Acute Kidney Injury: Epidemiology, Pathophysiology, Diagnosis, and Management
Chapter 11 Acute Kidney Failure and Minimal Change Disease
Chapter 12 Core Concepts: Post-Cardiac Surgery Acute Kidney Injury
Chapter 13 Rare and Overlooked Causes of Acute Kidney Injury
Chapter 14 Acute Kidney Injury in Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment
Chapter 15 Pediatric Acute Kidney Injury: Diagnosis, Epidemiology, and Treatment
Chapter 16 Post-Renal Acute Kidney Injury: Epidemiology, Presentation, Pathophysiology, Diagnosis, and Management
Chaper 17 Cardiorenal Acute Kidney Injury: Epidemiology, Presentation, Causes, Pathophysiology and Treatment
Chapter 18 Perioperative (non-cardiac) Acute Kidney Injury: Epidemiology, Pathophysiology, Prevention, and Treatment

Part IV Management

Chapter 19 Non-Dialytic Management of Acute Kidney Injury
Chapter 20 Diuretics in Acute Kidney Injury
Chapter 21 Emerging Therapies for Acute Kidney Injury: What's on the Horizon?
Chapter 22 Dialytic Therapy of Acute Kidney Injury
Chapter 23 Drug Dosing in Acute Kidney Injury

This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.

Ajay K. Singh, MB, MRCP, MBA, Renal Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA

Sushrut S. Waikar, MD, MPH, Renal Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA

Patrick Murray, MDDean of Medicine & Head of SchoolUniversity College Dublin School of Medicine & Medical ScienceDublin, Ireland