


Forensic DNA Applications. An Interdisciplinary Perspective
Primorac, D. — Schanfield, M.
1ª Edición Enero 2014
Inglés
Tapa dura
647 pags
1900 gr
x x cm
ISBN 9781466580220
Editorial CRC PRESS
Recíbelo en un plazo De 2 a 3 semanas
Description
Forensic DNA Applications: An Interdisciplinary Perspective was developed as
an outgrowth of a conference held by the International Society of Applied Biological
Sciences. The topic was human genome–based applications in forensic science,
anthropology, and individualized medicine. Assembling the contributions of contributors
from numerous regions around the world, this volume is designed as both a textbook
for forensic molecular biology students and a reference for practitioners and
those in the legal system.
The book begins with the history and development of DNA typing and profiling
for criminal and civil purposes. It discusses the statistical interpretation
of results with case examples, mitochondrial DNA testing, Y single nucleotide
polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing.
It also explores low copy number DNA typing, mixtures, and quality assurance
and control.
The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany.
The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics.
The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
Contents
General Background and Methodological Concepts
Basic Genetics and Human Genetic Variation; Dragan Primorac, Moses S. Schanfield,
and Damir Marjanovic
Forensic DNA Analysis and Statistics; Moses S. Schanfield, Dragan Primorac,
and Damir Marjanovic
Forensic Aspects of mtDNA Analysis; Mitchell M. Holland and Gordan Lauc
Y Chromosome in Forensic Science; Manfred Kayser and Kaye N. Ballantyne
Forensic Application of X Chromosome STR s and SNPs; Toni Marie Diegoli
Low Copy Number DNA Profiling; Theresa Caragine, Krista Currie, and Craig O’Connor
Forensic DNA Mixtures, Approaches, and Analysis; Theresa Caragine, Adele Mitchell,
and Craig O’Connor
Forensic DNA Typing and Quality Assurance; Daniel Vanek and Katja Drobnic
Uses and Applications
Collection and Preservation of Physical Evidence; Henry Lee, Timothy Palmbach,
Dragan Primorac, and Šimun Andelinovic
Identification of Missing Persons and Mass Disaster Victim Identification by
DNA; Barbara A. Butcher, Frederick R. Bieber, Zoran M. Budimlija, Sheila M.
Dennis, and Mark A. Desire
Bioterrorism and Forensic Microbiology; Alemka Markotic, James W. LeDuc, and
Jenifer Smith
Forensic Animal DN A Analysis; Marilyn A. Menotti-Raymond, Victor A. David,
Stephen J. O’Brien, Sree Kanthaswamy, Petar Projic, Vedrana Škaro,
Gordan Lauc, and Adrian Linacre
Application of DN A- Based Methods in Forensic Entomology; Jeffrey D. Wells
and Vedrana Škaro
Forensic Botany: Plants as Evidence in Criminal Cases and as Agents of Bioterrorism;
Heather Miller Coyle, Henry C. Lee, and Timothy M. Palmbach
Recent Developments and Future Directions in Human Forensic Molecular
Biology
Forensic Tissue Identification with Nucleic Acids; Dmitry Zubakov and Manfred
Kayser
Evolving Technologies in Forensic DNA Analysis; Cassandra D. Calloway and Henry
Erlich
Prediction of Physical Characteristics, such as Eye, Hair, and Skin Color Based
Solely on DNA; Elisa Wurmbach
Molecular Autopsy; Grace Axler-DiPerte, Frederick R. Bieber, Zoran Budimlija,
Antii Sajantila, Donald Siegel, and Yingying Tang
Genetic Genealogy in Genomic Era; Jake Byrnes, Natalie M. Myres, and Peter A.
Underhill
Law, Ethics, and Policy
DNA as Evidence in the Courtroom; David H. Kaye, Frederick R. Bieber, and Damir
Primorac
Some Ethical Issues in Forensic Genetics; Erin D. Williams and David H. Kaye
DNA in Immigration and Human Trafficking; Sara Huston Katsanis and Joyce Kim
DNA Databanking; Chris Asplen
Index
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