This standard-setting textbook has defined the field of immunology since 1984,
and is now in its Seventh Edition continuing to deliver the detailed, authoritative,
and timely coverage readers expect. This comprehensive, up-to-date text is ideal
for graduate students, post-doctoral fellows, basic and clinical immunologists,
microbiologists and infectious disease physicians, and any physician treating
diseases in which immunologic mechanisms play a role.
Now full-color throughout the book’s fully revised and updated content reflects the latest advances in the field. Current insights enhance readers’ understanding of immune system function. The text’s unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank!
Look inside and discover…
• Fully revised and updated content reflects the latest advances in the field.
• Current insights enhance readers’ understanding of immune system function
• Unique approach bridges the gap between basic immunology and the disease process.
• Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment.
• Abundant illustrations and tables deliver essential information at a glance.
A convenient companion website features the fully searchable text and image bank!
Table of contents
Section I. Introduction to Immunology 1 The Immune System William E. Paul 2 History of Immunology Steven Greenberg Section II. Organization and Evolution of the Immune System 3 Lymphoid Tissues and Organs Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle 4 Evolution of the Immune System Martin F. Flajnik Section III. Immunoglobulins and B Lymphocytes 5 Immunoglobulins: Structure and Function Harry W. Schroeder 6 Immunoglobulins: Molecular Genetics Edward E. Max and Sebastian Fugmann 7 Antigen-Antibody Reactions Jay A. Berzofsky and Ira Berkower 8 B Lymphocyte Development Richard R. Hardy 9 B Lymphocyte Receptors, Signaling Mechanisms, and Activation Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce 10 B Lymphocyte Responses Michael McHeyzer-Williams Section IV. T Lymphocytes 11 T Lymphocyte Receptors Mark M. Davis 12 T Lymphocyte Signaling Mechanisms Takashi Saito 13 T Lymphocyte Developmental Biology Ellen V. Rothenberg and Ameya Champhekar 14 Peripheral T Lymphocyte Responses and Function Marc K. Jenkins Section V. The Intersection of Innate and Adaptive Immunity 15 The Innate Immune System Luke A. J. Oâ€™Neill 16 Dendritic Cells Michel C. Nussenzweig 17 Natural Killer Cells Wayne M. Yokoyama 18 CD1d-restricted NKT Cells Albert S. Bendelac 19 Macrophages and Phagocytosis Siamon Gordon 20 Granulocytes and Mast Cells Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella 21 The Major Histocompatibility Complex and its Proteins David H. Margulies 22 Antigen Processing and Presentation Ted H. Hansen and Paul A. Roche Section VI. Induction, Regulation, and Effector Functions of the Immune Response 23 Immunogenicity and Antigen Structure Jay A. Berzofsky 24 Fc Receptors and Their Role in Immune Regulation and Inflammation Jeffrey V. Ravetch and Falk Nimmerjahn 25 Type I Cytokines and Interferons Warren J. Leonard 26 Interleukin-1 Family Cytokines Charles A. Dinarello and Mihai G. Netea 27 TNF-related Cytokines in Immunity Carl F. Ware 28 Chemokines Philip M. Murphy 29 Helper T Cell Differentiation and Plasticity John J. Oâ€™Shea 30 Programmed Cell Death Andrew L. Snow and Michael J. Lenardo 31 Immunological Memory Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger 32 Immunological Tolerance Pamela S. Ohashi 33 Regulatory/Suppressor T Cells Ethan M. Shevach 34 Mucosal Immunity and Microbiome Yasmine Belkaid 35 Neurophysiological Reflex Mechanisms in Immunology Chavan and Kevin J. Tracey 36 Complement B. Paul Morgan 37 Cell-mediated Cytotoxicity Judy Lieberman Section VII. Immunity to Infectious Agents 38 The Immune Response to Parasites Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley