Origin of Cancers. Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer

About this book

The theory of a stem-cell origin of cancer is neither ground breaking nor earth shattering. Many prominent investigators have established the foundation for this concept and performed the vital experiments to support its validity and merit. The purpose of this book is to illustrate how this theory may completely transform our current views and perspectives about cancer. It is anticipated that the variety of ramifications of a stem-cell origin of cancers will be embraced by the medical research community to bring new treatment modalities to the cancer patient.

"The stem-cell theory of cancer has significant biologic and clinical consequences. Though components remain open to debate the fundamental observations are grounded in scientific experimentation. This text explains the conceptual aspects of cancer stem cells with an emphasis on the implications for our patients."

- Steven T. Rosen, M.D.
Series Editor

Content Level » Professional/practitioner
Keywords » Heterogeneity - Metastasis - Neoplasm - Tumors
Related subjects » Cancer Research - Human Genetics - Oncology & Hematology

Table of contents

1.Introduction
2.Cancer myths
3.History of cancer
4.Origin of cancer
5.Stem cells
6.Stem cells and cancer
7.Cancer stem cells
8.Cancer niche
9.Ontogeny and oncology
10.Diagnosis and prognosis
11.Cancer targets
12.Heterogeneity of cancer
13.Metastasis
14.Cancer immunity
15.Drug resistance
16.Paradigm shifts
17.Experimental proof
18.Clinical implications
19.Curing cancer
20.Epilogue