Pharmaceutical Powder Compaction Technology

Reflecting modern pharmaceutical compacting techniques, this text guides pharmaceutical engineers, formulation scientists, and product development/quality assurance personnel through the compaction formulation process.

Compaction of powder constituents is examined to ensure consistent and reproducible disintegration and dispersion profiles.

Topics:

• the physical structure of pharmaceutical compacts
• bonding phenomena occuring during powder compaction
• compression mechanisms of pharmaceutical particles
• theories/basic principles of powder compaction

New topics:

• compaction data analysis techniques
• migration of powder constituents to commercial manufacture
• instrumentation for compaction
• compaction functionality testing
• design space for compaction
• metrics for scalability in tablet compression
• interactive compaction and preformulation database for common excipients