An international group of experts in drug development and biopharmaceutical science discusses the latest in biodrug delivery systems and associated techniques.
It explores components of successful formulation, delivery, and production of biodrugs, including:
- sophisticated plants
- complex processes
- a well-trained and knowledgeable staff
- proper quality control
Other topics include:
- AMDE (Absorption, Metabolism, Distribution, and Excretion of biodrugs)
- successful development of currently marketed best-selling biodrugs
- routes of administration
- mechanisms of biodrug absorption
- alternative drug delivery routes
- formulations on the market
Overview of Biodrug delivery system. Issues in Biodrug delivery system. Pharmacokinetic consideration of Biodrugs. Specific Route of Delivery. Parenteral delivery. Brain delivery. Ocular delivery. Nasal delivery. Buccal delivery. Pulmonary delivery. Transdermal delivery. Colon delivery. Oral delivery. Cellular delivery. Delivery Systems. Targeting: PK consideration. Monoclonal antibody. Receptor-mediated endocytosis. Bioadhesive delivery system. Modified release delivery system. Nanoparticulate delivery system. Lipid-based delivery system. Implantable delivery system. Modifying the physiochemical nature of Biodrugs. Regulatory perspective of Biodrug development. Development of Biodrug Products. Leuplin. ANP (atrial natriuretic peptide). Amylin and GLP-1 agonists. GHRP-2 (growth hormone releasing peptide. Endothelin receptor antagonist. Angiotensin II receptor antagonist. Insulin (inhalation). Calcitonin (nasal, etc.) Sandstatin LAR. Interferon. Vaccine. Perspective of Biodrug Products.
ABOUT THE EDITOR(S)/AUTHOR(S):
Dr. Morisita is Associate Professor of Pharmaceutics, Hoshi University, Japan. She is on the Councils of the Academy of Pharmaceutical Sciences and Technology, Japan, and the Japan Society of Drug Delivery Systems. Dr. Morisita is also Board of Scientific Advisor of CRS. She has coauthored 70 international journal publications, 150 abstracts, and 4 books.
Dr. Park is Professor of Pharmaceutics and Showalter Distinguished Professor of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA. He is the coauthor of eight international journal articles.