Now in its third edition, this "benchside" reference provides you with a structured diagnostic approach to the features of the placenta most commonly encountered in the investigation of adverse fetal outcomes. Inside, you'll find detailed disussions on cytogenetics and molecular biology as well as the latest developments in coagulopathy, infections, chorioamnionitis, preeclampsia, trophoblastic disease, and twin pregnancies among others. Plus, a new format facilitates information retrieval and new color clinical and pathologic images help you recognize and disagnose lesions better than ever.
BMA Book Awards 2008 - Commended
"What is, for many people, one of the least exciting subjects in pathology, the examination of the placenta, has produced one of the best written texts. There is, in the writing of Professor Fox and his co-author Dr Sebire, a limpidity, concision, and erudition (the term 'succenturiate' is dismissed with a note on the proper meaning of 'succinere') lacking in many other textbooks of histology. There is also much common sense, as the authors consistently resist the temptation, endemic among placental pathologists, of investing every lesion, however trivial, with unwarranted importance. Despite the book's convincing argument that routine weighing of the placenta is 'of little value', the practice, and other such 'genuflexions towards the altar of scientific measurement' continues; this book is an encouragement to all surgical pathologists to consider the true evidence base rather than any arbitrary data set. Pathologists familiar with previous editions will find themselves at home with this latest, which has been carefully updated without any radical, unsettling alterations. For day-to-day reporting of placental histology, this book is the best available and its clarity of style and layout encourage frequent consultation. From the sections on the anatomy and physiology of the placenta, medicolegal aspects of placental pathology and ultrasound findings, one can learn much to make examination of the placenta a more rewarding experience."
Highly Commended at The Royal Society of Medicine & The Society of Authors’ Medical Book Awards
“This is a unique book…a marvellous compendium of fetal pathology and physiology as well as placental pathology…beautifully written, this is a superb book. A real classic and a joy to read.”
- Access the most authoritative and effective diagnostic help with step-by-step guidance on placental examination techniques.
- Get the clinical information you need without superfluous details.
- Create better reports or prepare for exams with comprehensive coverage of all benign and malignant disorders of placental abnormalities.
New to this Edition
- Increase your diagnostic acumen with new and expanded topics such as apoptosis in the normal and pathological placenta, pathogenesis of miscarrage, placental infections (especially malaria and HIV), chorioanmionitis with special reference to its role in cerebral palsy, preeclampsia, gestational trophoblastic disease, medico-legal aspects of the placenta, and much more.
- Perform a complete diagnostic workup with detailed coverage of molecular biology, immunohistochemisrty, and cytogenetics.
- Diagnose confidently with the addition of full-color images throughout.
- Find the the information you need quickly thanks to a new user-friendly format, including bullet points, summary tables, and take-home messages.
Table of Contents
- The Development of the Placenta
- Physiology of the Placenta
- Abnormalities of Placentation
- The Placenta in Multiple Pregnancy
- Macroscopic Abnormalities of the Placenta
- Histological Abnormalities of the Placenta
- The Placenta in Pregnancies of Abnormal Duration
- The Placenta in Maternal Disorders
- The Placenta in Abnormalities and Disorders of the Fetus
- The Placenta in Abortion
- Infections and Inflammatory Lesions of the Placenta
- Immunopathology of the Placenta
- Non-Trophoblastic Tumours of the Placenta
- Gestational Trophoblastic Disease
- Pathology of the Umbilical Cord
- Pathology of the Membranes
- Pathological Examination of the Placenta
- Placental Weight
- Placental Biopsy
- Medico-Legal Aspects of Placental Pathology
By Harold Fox, MD, FRCPath, FRCOG, Emeritus Professor of Reproductive Pathology, Department of Pathological Sciences, The University of Manchester, Manchester, UK; and Neil Sebire, MB, BS, FRCPath, Consultant Pathologist, Great Ormond Street Children's Hospital, London, UK