This book in the new American Heart Association Clinical Series, explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy. Skillfully organized for fast reference, the book is divided into five parts:
- Concepts in Platelet Physiology, Function, and Measurement
- Pharmacology of Oral Antiplatelet Agents
- Pharmacology of Intravenous Antiplatelet Agents
- Clinical Use of Antiplatelet Agents in Cardiovascular Disease
- Special Circumstances.
Each chapter in the clinical section contains an overview of guidelines, plus specifics on medical and interventional uses.
Clinical cardiologists, platelet biologists, and a wide range of practicing and prospective clinicians in allied fields will find this text an exceptional source of current information.
Table of Contents
Part I Concepts in Platelet Physiology, Function and Measurement.
1 Platelet physiology and the role of the platelet in ischemic heart disease.
Robert F. Storey .
2 Laboratory assessment of platelet function and the effects of antiplatelet
Alan D. Michelson, A.L. Frelinger .
Part II Pharmacology of Oral Antiplatelet Agents.
3 Cyclooxygenase inhibitors.
Nina Chetty Raju, John W. Eikelboom .
4 Aspirin response variability and resistance.
Wai-Hong Chen, Daniel I. Simon .
5 P2Y12 inhibitors: Thienopyridines and direct oral inhibitors.
Jean-Philippe Collet, Boris Aleil, Christian Gachet, Gilles Montalescot .
6 Thienopyridine response variability and resistance.
Udaya S. Tantry, Thomas A. Suarez, Paul A. Gurbel .
Part III Pharmacology of Intravenous Antiplatelet Agents.
7 Pharmacology of intravenous glycoprotein IIb/IIIa antagonists.
James C. Blankenship, Peter B. Berger .
8 Intravenous P2Y12 inhibitors.
Steven P. Dunn, Steven R. Steinhubl .
9 Antiplatelet effects of thrombin inhibitors and fibrinolytic agents.
Nicolai Mejevoi, Anjum Tanwir, Marc Cohen .
Part IV Clinical Use of Antiplatelet Agents in Cardiovascular Disease.
10 Antiplatelet therapy in acute coronary syndrome with ST elevation.
Christian W. Hamm .
11 Antiplatelet therapy in ST-elevation myocardial infarction.
Michelle O'Donoghue, Marc S. Sabatine .
12 Antiplatelet therapy in chronic artery disease.
Kamran I. Muhammed, Deepak L. Bhatt .
13 Antiplatelet therapy in peripheral arterial disease.
Esther S. Kim, Heather L. Gornik .
14 Clinical use of antiplatelet agents in cardiovascular disease: cerebrovascular
Larry B. Goldstein .
Part V Special Circumstances.
15 Antiplatelet therapy and coronary bypass surgery: risks and benefits.
A. Burdess, N.L. Cruden, K.A. Fox .
16 Management of antiplatelet therapy for non-cardiac surgery.
Nisheeth Goel, John F. Canales, James J. Ferguson .
17 Antiplatelet therapy and coronary stents.
Alanna Coolong, Laura Mauri
Stephen D. Wiviott, MD., Investigator TIMI Study Group, Associate Physician,
Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA